Gang Lin

Holistic Medicine

4011 Murray St
Flushing, NY 11354

Last Updated: 09/26/2026

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Found 35 publications

Intracellular Activation of Dual-Pharmacophore Artezomib Enhances Selective Cytotoxicity in Hematologic Malignancies.

Intracellular Activation of Dual-Pharmacophore Artezomib Enhances Selective Cytotoxicity in Hematologic Malignancies.

Journal: Journal of medicinal chemistry

Published: May 02, 2026

CDK4/6 Inhibition Reverses MEIS2 Suppression of CRL4 CRBN to Enhance Immunomodulatory Drug Therapy in Multiple Myeloma.

CDK4/6 Inhibition Reverses MEIS2 Suppression of CRL4 CRBN to Enhance Immunomodulatory Drug Therapy in Multiple Myeloma.

Journal: bioRxiv : the preprint server for biology

Published: November 24, 2025

The immunoproteasome regulates ILC2 responses by modulating mitochondrial capacity.

The immunoproteasome regulates ILC2 responses by modulating mitochondrial capacity.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: November 20, 2025

A recombinant expression system for the Plasmodium falciparum proteasome enables structural analysis of its assembly and the design of selective inhibitors.

A recombinant expression system for the Plasmodium falciparum proteasome enables structural analysis of its assembly and the design of selective inhibitors.

Journal: bioRxiv : the preprint server for biology

Published: August 20, 2025

Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum.

Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum.

Journal: ACS infectious diseases

Published: September 15, 2023

Protocol for analysis of intracellular conversion of artezomib molecules into new proteasome inhibitors in Plasmodium falciparum parasites.

Protocol for analysis of intracellular conversion of artezomib molecules into new proteasome inhibitors in Plasmodium falciparum parasites.

Journal: STAR protocols

Published: July 20, 2023

Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors.

Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors.

Journal: Nature communications

Published: May 30, 2023

High-Throughput/High Content Imaging Screen Identifies Novel Small Molecule Inhibitors and Immunoproteasomes as Therapeutic Targets for Chordoma.

High-Throughput/High Content Imaging Screen Identifies Novel Small Molecule Inhibitors and Immunoproteasomes as Therapeutic Targets for Chordoma.

Journal: Pharmaceutics

Published: February 06, 2023

Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II.

Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II.

Journal: Journal of medicinal chemistry

Published: January 11, 2023

Discovery of Highly Selective Inhibitors of the Human Constitutive Proteasome β5c Chymotryptic Subunit.

Discovery of Highly Selective Inhibitors of the Human Constitutive Proteasome β5c Chymotryptic Subunit.

Journal: Journal of medicinal chemistry

Published: January 06, 2023

Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome.

Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome.

Journal: Cell chemical biology

Published: November 15, 2022

Structure of the human UBR5 E3 ubiquitin ligase.

Structure of the human UBR5 E3 ubiquitin ligase.

Journal: Structure (London, England : 1993)

Published: November 15, 2022

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Last Updated: 09/26/2026