Gaona L. Shi

State Key Laboratory Of Bioactive Substance And Function Of Natural Medicines, Chinese Academy Of Medical Sciences & Peking Union Medical College
Beijing, 100050, China

Last Updated: 09/26/2026

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Found 28 publications

Immunomodulatory supramolecular hydrogel for rheumatoid arthritis management via adenosine A2A receptor-mediated macrophage remodeling.

Immunomodulatory supramolecular hydrogel for rheumatoid arthritis management via adenosine A2A receptor-mediated macrophage remodeling.

Journal: Bioactive materials

Published: August 20, 2025

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte-Macrophage Crosstalk.

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte-Macrophage Crosstalk.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: July 09, 2025

Fine-tuning of stable organic free-radical photosensitizers for photodynamic immunotherapy.

Fine-tuning of stable organic free-radical photosensitizers for photodynamic immunotherapy.

Journal: Chemical science

Published: December 19, 2023

Unravelling Immune-Inflammatory Responses and Lysosomal Adaptation: Insights from Two-Photon Excited Delayed Fluorescence Imaging.

Unravelling Immune-Inflammatory Responses and Lysosomal Adaptation: Insights from Two-Photon Excited Delayed Fluorescence Imaging.

Journal: Advanced healthcare materials

Published: November 29, 2023

A synthetic derivative of bioactive constituents from Isatis indigotica ameliorates hypersensitivity and arthritis by inhibiting JAK2-STAT3 pathway in mice.

A synthetic derivative of bioactive constituents from Isatis indigotica ameliorates hypersensitivity and arthritis by inhibiting JAK2-STAT3 pathway in mice.

Journal: International immunopharmacology

Published: June 02, 2023

JAK inhibition ameliorated experimental autoimmune encephalomyelitis by blocking GM-CSF-driven inflammatory signature of monocytes.

JAK inhibition ameliorated experimental autoimmune encephalomyelitis by blocking GM-CSF-driven inflammatory signature of monocytes.

Journal: Acta pharmaceutica Sinica. B

Published: March 15, 2023

Bone-derived MSCs encapsulated in alginate hydrogel prevent collagen-induced arthritis in mice through the activation of adenosine A2A/2B receptors in tolerogenic dendritic cells.

Bone-derived MSCs encapsulated in alginate hydrogel prevent collagen-induced arthritis in mice through the activation of adenosine A2A/2B receptors in tolerogenic dendritic cells.

Journal: Acta pharmaceutica Sinica. B

Published: February 02, 2023

Celastrol Targets Cullin-Associated and Neddylation-Dissociated 1 to Prevent Fibroblast-Myofibroblast Transformation against Pulmonary Fibrosis.

Celastrol Targets Cullin-Associated and Neddylation-Dissociated 1 to Prevent Fibroblast-Myofibroblast Transformation against Pulmonary Fibrosis.

Journal: ACS chemical biology

Published: September 08, 2022

A highly selective JAK3 inhibitor is developed for treating rheumatoid arthritis by suppressing γc cytokine-related JAK-STAT signal.

A highly selective JAK3 inhibitor is developed for treating rheumatoid arthritis by suppressing γc cytokine-related JAK-STAT signal.

Journal: Science advances

Published: August 19, 2022

Therapeutic potential of the target on NLRP3 inflammasome in multiple sclerosis.

Therapeutic potential of the target on NLRP3 inflammasome in multiple sclerosis.

Journal: Pharmacology & therapeutics

Published: December 31, 2020

Exploring a novel triptolide derivative possess anti-colitis effect via regulating T cell differentiation.

Exploring a novel triptolide derivative possess anti-colitis effect via regulating T cell differentiation.

Journal: International immunopharmacology

Published: June 26, 2020

A novel triptolide derivative ZT01 exerts anti-inflammatory effects by targeting TAK1 to prevent macrophage polarization into pro-inflammatory phenotype.

A novel triptolide derivative ZT01 exerts anti-inflammatory effects by targeting TAK1 to prevent macrophage polarization into pro-inflammatory phenotype.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: February 04, 2020

Showing 1-12 of 28

Last Updated: 09/26/2026