Gaoyun Y. Hu

Changsha, 410013, China

Last Updated: 09/26/2026

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Found 67 publications

A Novel Dual URAT1/GLUT9 Inhibitor Reduces Hyperuricemia by Enhancing Uric Acid Excretion and Attenuating Renal Fibrosis.

A Novel Dual URAT1/GLUT9 Inhibitor Reduces Hyperuricemia by Enhancing Uric Acid Excretion and Attenuating Renal Fibrosis.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: February 08, 2026

Novel 2,4-thiazolidinedione derivatives as selective AMPKα1 activators for renal ischemia-reperfusion injury therapeutics.

Novel 2,4-thiazolidinedione derivatives as selective AMPKα1 activators for renal ischemia-reperfusion injury therapeutics.

Journal: European journal of medicinal chemistry

Published: October 06, 2025

Pan-Cdk inhibitor ZK304709 suppresses Cdc20 expression and potentiates the anticancer activity of apcin in HeLa cervical cancer cells.

Pan-Cdk inhibitor ZK304709 suppresses Cdc20 expression and potentiates the anticancer activity of apcin in HeLa cervical cancer cells.

Journal: Acta pharmaceutica (Zagreb, Croatia)

Published: October 05, 2025

Design, synthesis and optimization of Apcin analogues as Cdc20 inhibitors for triple-negative breast cancer therapy.

Design, synthesis and optimization of Apcin analogues as Cdc20 inhibitors for triple-negative breast cancer therapy.

Journal: European journal of medicinal chemistry

Published: December 29, 2024

Fluorofenidone attenuates choline-deficient, l-amino acid-defined, high-fat diet-induced metabolic dysfunction-associated steatohepatitis in mice.

Fluorofenidone attenuates choline-deficient, l-amino acid-defined, high-fat diet-induced metabolic dysfunction-associated steatohepatitis in mice.

Journal: Scientific reports

Published: November 11, 2024

Mefunidone treats pulmonary fibrosis by targeting SDH to regulate fibro-promoting macrophages.

Mefunidone treats pulmonary fibrosis by targeting SDH to regulate fibro-promoting macrophages.

Journal: International immunopharmacology

Published: August 16, 2024

Chromone Derivatives as a Novel NOX4 Inhibitor: Design, Synthesis, and Regulation of ROS in Renal Fibroblast.

Chromone Derivatives as a Novel NOX4 Inhibitor: Design, Synthesis, and Regulation of ROS in Renal Fibroblast.

Journal: Chemical biology & drug design

Published: August 03, 2024

Mefunidone alleviates silica-induced inflammation and fibrosis by inhibiting the TLR4-NF-κB/MAPK pathway and attenuating pyroptosis in murine macrophages.

Mefunidone alleviates silica-induced inflammation and fibrosis by inhibiting the TLR4-NF-κB/MAPK pathway and attenuating pyroptosis in murine macrophages.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: May 21, 2024

A phase I, randomized study to evaluate the safety, tolerability, and pharmacokinetics of mefunidone in healthy subjects.

A phase I, randomized study to evaluate the safety, tolerability, and pharmacokinetics of mefunidone in healthy subjects.

Journal: Frontiers in pharmacology

Published: April 08, 2024

Design, Synthesis, and Biological Evaluation of Quinoline (Quinolinone) Derivatives as NADPH Oxidase (NOX) Inhibitors.

Design, Synthesis, and Biological Evaluation of Quinoline (Quinolinone) Derivatives as NADPH Oxidase (NOX) Inhibitors.

Journal: Chemical biology & drug design

Published: March 04, 2024

Surgical treatment of nasopharyngeal cancer - a consensus recommendation from two Chinese associations.

Surgical treatment of nasopharyngeal cancer - a consensus recommendation from two Chinese associations.

Journal: Rhinology

Published: October 30, 2023

Inhibition of Hsp110-STAT3 interaction in endothelial cells alleviates vascular remodeling in hypoxic pulmonary arterial Hypertension model.

Inhibition of Hsp110-STAT3 interaction in endothelial cells alleviates vascular remodeling in hypoxic pulmonary arterial Hypertension model.

Journal: Respiratory research

Published: September 16, 2023

Showing 1-12 of 67

Last Updated: 09/26/2026