Gareth E. Lim

Montreal, QC, Canada

Last Updated: 09/26/2026

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Found 28 publications

β-cell 14-3-3-ζ and sex are key regulators of α-cell form and function.

β-cell 14-3-3-ζ and sex are key regulators of α-cell form and function.

Journal: Endocrinology

Published: May 21, 2026

Adipocyte-specific ablation of plakoglobin in mice does not affect adiposity but results in sexual-dimorphic effects on weight gain.

Adipocyte-specific ablation of plakoglobin in mice does not affect adiposity but results in sexual-dimorphic effects on weight gain.

Journal: Physiological reports

Published: May 10, 2025

14-3-3ζ allows for adipogenesis by modulating chromatin accessibility during the early stages of adipocyte differentiation.

14-3-3ζ allows for adipogenesis by modulating chromatin accessibility during the early stages of adipocyte differentiation.

Journal: Molecular metabolism

Published: March 26, 2025

A high-throughput screening approach to discover potential colorectal cancer chemotherapeutics: repurposing drugs to identify novel disruptors of 14-3-3 proteins.

A high-throughput screening approach to discover potential colorectal cancer chemotherapeutics: repurposing drugs to identify novel disruptors of 14-3-3 proteins.

Journal: Cell death & disease

Published: October 14, 2024

Corrigendum to "Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells" [Mol Metab 2016 May; 5 (5): 366-378].

Corrigendum to "Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells" [Mol Metab 2016 May; 5 (5): 366-378].

Journal: Molecular metabolism

Published: April 11, 2024

14-3-3ζ regulates adipogenesis by modulating chromatin accessibility during the early stages of adipocyte differentiation.

14-3-3ζ regulates adipogenesis by modulating chromatin accessibility during the early stages of adipocyte differentiation.

Journal: bioRxiv : the preprint server for biology

Published: April 02, 2024

A high-throughput screening approach to discover potential colorectal cancer chemotherapeutics: Repurposing drugs to disrupt 14-3-3 protein-BAD interactions.

A high-throughput screening approach to discover potential colorectal cancer chemotherapeutics: Repurposing drugs to disrupt 14-3-3 protein-BAD interactions.

Journal: bioRxiv : the preprint server for biology

Published: January 03, 2024

Plakoglobin regulates adipocyte differentiation independently of the Wnt/β-catenin signaling pathway.

Plakoglobin regulates adipocyte differentiation independently of the Wnt/β-catenin signaling pathway.

Journal: Biochimica et biophysica acta. Molecular cell research

Published: August 25, 2023

Is 14-3-3 the Combination to Unlock New Pathways to Improve Metabolic Homeostasis and β-Cell Function?

Is 14-3-3 the Combination to Unlock New Pathways to Improve Metabolic Homeostasis and β-Cell Function?

Journal: Diabetes

Published: February 03, 2023

The Application of High-Throughput Approaches in Identifying Novel Therapeutic Targets and Agents to Treat Diabetes.

The Application of High-Throughput Approaches in Identifying Novel Therapeutic Targets and Agents to Treat Diabetes.

Journal: Advanced biology

Published: May 31, 2022

14-3-3ζ Constrains insulin secretion by regulating mitochondrial function in pancreatic β cells.

14-3-3ζ Constrains insulin secretion by regulating mitochondrial function in pancreatic β cells.

Journal: JCI insight

Published: November 03, 2021

Metabolic Contributions of Wnt Signaling: More Than Controlling Flight.

Metabolic Contributions of Wnt Signaling: More Than Controlling Flight.

Journal: Frontiers in cell and developmental biology

Published: May 14, 2021

Showing 1-12 of 28

Last Updated: 09/26/2026