Gehan H. Heeba
Al Minya, MN, Egypt
Last Updated: 09/26/2026
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Found 44 publications
Diacerein Ameliorates Gentamicin-Induced Nephrotoxicity via Regulating PI3k/AKT-Mediated Nrf-2 and NF-κB Pathways: Forge the Mechanistic Insight.
Journal: Journal of biochemical and molecular toxicology
Published: December 04, 2025
Empagliflozin mitigates doxorubicin-induced nephrotoxicity by modulating sirtuin 1, nuclear factor-κB/tumor necrosis factor-α, and cleaved caspase-3 pathways without compromising its cytotoxic efficacy.
Journal: The Journal of pharmacology and experimental therapeutics
Published: October 18, 2025
Modulation of SIRT-1, NF-κB/TNF-α/IL-6, and ERK/Caspase-3 by Lutein Mitigates Methotrexate-Induced Hepatotoxicity.
Journal: Pharmaceuticals (Basel, Switzerland)
Published: October 15, 2025
Alogliptin Mitigates Methotrexate-Induced Nephrotoxicity in a Rat Model: Antagonizing Oxidative Stress, Inflammation and Apoptosis.
Journal: International journal of molecular sciences
Published: August 07, 2025
Insights Into the Ameliorative Effect of Diacerein on Cyclophosphamide-Induced Testicular Toxicity: Targeting TLR4/NF-κB/IL-1β Pathway.
Journal: Journal of biochemical and molecular toxicology
Published: April 17, 2025
Morin hydrate alleviated cisplatin-induced testicular toxicity in rats via modulating NLRP3/NF-κB pathway.
Journal: Naunyn-Schmiedeberg's archives of pharmacology
Published: March 13, 2025
Gallic and glycyrrhetinic acids prevent azithromycin-induced liver damage in rats by mitigating oxidative stress and inflammation.
Journal: Scientific reports
Published: December 08, 2024
Modified citrus pectin ameliorates methotrexate-induced hepatic and pulmonary toxicity: role of Nrf2, galectin-3/TLR-4/NF-κB/TNF-α and TGF-β signaling pathways.
Journal: Frontiers in pharmacology
Published: November 15, 2024
Comparative effects of incretin-based therapy on doxorubicin-induced nephrotoxicity in rats: the role of SIRT1/Nrf2/NF-κB/TNF-α signaling pathways.
Journal: Frontiers in pharmacology
Published: December 09, 2023
Mechanistic Protective Effect of Cilostazol in Cisplatin-Induced Testicular Damage via Regulation of Oxidative Stress and TNF-α/NF-κB/Caspase-3 Pathways.
Journal: International journal of molecular sciences
Published: May 24, 2023
Hibiscus-cisplatin combination treatment decreases liver toxicity in rats while increasing toxicity in lung cancer cells via oxidative stress- apoptosis pathway.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: May 13, 2023
Dapoxetine prevents neuronal damage and improves functional outcomes in a model of ischemic stroke through the modulation of inflammation and oxidative stress.
Journal: Naunyn-Schmiedeberg's archives of pharmacology
Published: February 26, 2023
Last Updated: 09/26/2026