Last Updated: 09/26/2026
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Found 20 publications
Diazepam Relaxes Murine Peripheral Airway Smooth Muscle Through Inhibition of Phosphodiesterase 4 and Intracellular Calcium Oscillations.
Journal: American journal of respiratory cell and molecular biology
Published: December 23, 2025
Development of novel pegylated imidazobenzodiazepines as inhaled asthma drug candidates.
Journal: Respiratory medicine
Published: August 28, 2025
Design, Synthesis, and Biological Evaluation of Novel Spiro Imidazobenzodiazepines to Identify Improved Inhaled Bronchodilators.
Journal: Journal of medicinal chemistry
Published: July 07, 2023
Imidazobenzodiazepine PI320 Relaxes Mouse Peripheral Airways by Inhibiting Calcium Mobilization.
Journal: American journal of respiratory cell and molecular biology
Published: July 01, 2022
Comparative pharmacodynamic and pharmacokinetic study of MIDD0301 and its (S) enantiomer.
Journal: Drug development research
Published: December 20, 2021
Development of Inhaled GABAA Receptor Modulators to Improve Airway Function in Bronchoconstrictive Disorders.
Journal: ACS pharmacology & translational science
Published: November 02, 2021
Nebulized MIDD0301 Reduces Airway Hyperresponsiveness in Moderate and Severe Murine Asthma Models.
Journal: ACS pharmacology & translational science
Published: October 27, 2020
Reduced allergic lung inflammation and airway responsiveness in mice lacking the cytoskeletal protein gelsolin.
Journal: American journal of physiology. Lung cellular and molecular physiology
Published: September 09, 2020
Ginger and its bioactive component 6-shogaol mitigate lung inflammation in a murine asthma model.
Journal: American journal of physiology. Lung cellular and molecular physiology
Published: December 05, 2019
Agonism of the TMEM16A calcium-activated chloride channel modulates airway smooth muscle tone.
Journal: American journal of physiology. Lung cellular and molecular physiology
Published: November 21, 2019
Correction to "A Novel Orally Available Asthma Drug Candidate That Reduces Smooth Muscle Constriction and Inflammation by Targeting GABAA Receptors in the Lung".
Journal: Molecular pharmaceutics
Published: October 22, 2019
A novel GABAA receptor ligand MIDD0301 with limited blood-brain barrier penetration relaxes airway smooth muscle ex vivo and in vivo.
Journal: American journal of physiology. Lung cellular and molecular physiology
Published: November 30, 2018
Last Updated: 09/26/2026