Gennady M. Butov - Publications

SAR exploration for 4-aminotetrahydroquinazolines with adamantyl moiety against orthoflaviviruses.

Journal: Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents

Published: January 26, 2026

1,3-Dichloroadamantyl-Containing Ureas as Potential Triple Inhibitors of Soluble Epoxide Hydrolase, p38 MAPK and c-Raf.

Journal: International journal of molecular sciences

Published: November 24, 2023

Fluorine and chlorine substituted adamantyl-urea as molecular tools for inhibition of human soluble epoxide hydrolase with picomolar efficacy.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: November 17, 2023

Adamantyl-ureas with pyrazoles substituted by fluoroalkanes as soluble epoxide hydrolase inhibitors.

Journal: Journal of fluorine chemistry

Published: August 28, 2023

Synthesis and Properties of 1,3-Disubstituted Ureas Containing (Adamantan-1-yl)(phenyl)methyl Fragment Based on One-Pot Direct Adamantane Moiety Inclusion.

Journal: Molecules (Basel, Switzerland)

Published: March 27, 2023

Anti-Inflammatory Activity of Soluble Epoxide Hydrolase Inhibitors Based on Selenoureas Bearing an Adamantane Moiety.

Journal: International journal of molecular sciences

Published: July 27, 2022

Ureas derived from camphor and fenchone reveal enantiomeric preference of human soluble epoxide hydrolase.

Journal: Results in chemistry

Published: January 01, 2022

Adamantyl Isothiocyanates as Mutant p53 Rescuing Agents and Their Structure-Activity Relationships.

Journal: Journal of medicinal chemistry

Published: May 07, 2021

Bioisosteric substitution of adamantane with bicyclic lipophilic groups improves water solubility of human soluble epoxide hydrolase inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: May 31, 2020

Fluoroaromatic fragments on 1,3-disubstituted ureas enhance soluble epoxide hydrolase inhibition.

Journal: Journal of fluorine chemistry

Published: March 06, 2020

Imidazolidine-2,4,5- and pirimidine-2,4,6-triones - New primary pharmacophore for soluble epoxide hydrolase inhibitors with enhanced water solubility.

Journal: Bioorganic & medicinal chemistry letters

Published: August 26, 2019

Tick-borne flavivirus reproduction inhibitors based on isoxazole core linked with adamantane.

Journal: Bioorganic chemistry

Published: December 11, 2018