George H. Kefalas

Intensive Care Medicine

2600 Tuscarawas St W Ste 100
Canton, OH 44708

Last Updated: 09/26/2026

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Found 6 publications

Negative regulation of the NF-κB pathway by the ubiquitin ligase Nedd4-1(NE).

Negative regulation of the NF-κB pathway by the ubiquitin ligase Nedd4-1(NE).

Journal: Communications biology

Published: May 20, 2025

The primate-specific Nedd4-1(NE) localizes to late endosomes in response to amino acids to suppress autophagy.

The primate-specific Nedd4-1(NE) localizes to late endosomes in response to amino acids to suppress autophagy.

Journal: Nature communications

Published: June 18, 2024

Primate-specific isoform of Nedd4-1 regulates substrate binding via Ser/Thr phosphorylation and 14-3-3 binding.

Primate-specific isoform of Nedd4-1 regulates substrate binding via Ser/Thr phosphorylation and 14-3-3 binding.

Journal: Scientific reports

Published: July 06, 2023

Elevated intracellular Na+ and osmolarity stimulate catalytic activity of the ubiquitin ligase Nedd4-2.

Elevated intracellular Na+ and osmolarity stimulate catalytic activity of the ubiquitin ligase Nedd4-2.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: July 20, 2022

Peptide-based sequestration of the adaptor protein Nck1 in pancreatic β cells enhances insulin biogenesis and protects against diabetogenic stresses.

Peptide-based sequestration of the adaptor protein Nck1 in pancreatic β cells enhances insulin biogenesis and protects against diabetogenic stresses.

Journal: The Journal of biological chemistry

Published: March 04, 2018

PERK leads a hub dictating pancreatic β cell homoeostasis.

PERK leads a hub dictating pancreatic β cell homoeostasis.

Journal: Biology of the cell

Published: October 11, 2017

Showing 1-6 of 6

Last Updated: 09/26/2026