George J. Fleet

Mansfield Road
Oxford, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 59 publications

Bacterial pathogen deploys the iminosugar glycosyrin to manipulate plant glycobiology.

Bacterial pathogen deploys the iminosugar glycosyrin to manipulate plant glycobiology.

Journal: Science (New York, N.Y.)

Published: April 17, 2025

Bacterial pathogen deploys iminosugar galactosyrin to manipulate plant glycobiology.

Bacterial pathogen deploys iminosugar galactosyrin to manipulate plant glycobiology.

Journal: bioRxiv : the preprint server for biology

Published: February 24, 2025

C-2 fluorinated castanospermines as potent and specific α-glucosidase inhibitors: synthesis and structure-activity relationship study.

C-2 fluorinated castanospermines as potent and specific α-glucosidase inhibitors: synthesis and structure-activity relationship study.

Journal: Organic & biomolecular chemistry

Published: February 20, 2025

Design and synthesis of 6-C-alkyl-DMDP type nanomolar inhibitors of β-galactosidase and β-glucosidase based on broussonetine S and related derivatives.

Design and synthesis of 6-C-alkyl-DMDP type nanomolar inhibitors of β-galactosidase and β-glucosidase based on broussonetine S and related derivatives.

Journal: European journal of medicinal chemistry

Published: April 26, 2024

Design and Pharmacological Chaperone Effects of N-(4'-Phenylbutyl)-DAB Derivatives Targeting the Lipophilic Pocket of Lysosomal Acid α-Glucosidase.

Design and Pharmacological Chaperone Effects of N-(4'-Phenylbutyl)-DAB Derivatives Targeting the Lipophilic Pocket of Lysosomal Acid α-Glucosidase.

Journal: Journal of medicinal chemistry

Published: June 14, 2023

Design and synthesis of iso-allo-DNJ and L-isoDALDP derivatives: pursuit of potent and selective inhibitors of α-glucosidase.

Design and synthesis of iso-allo-DNJ and L-isoDALDP derivatives: pursuit of potent and selective inhibitors of α-glucosidase.

Journal: Organic & biomolecular chemistry

Published: April 11, 2023

Design, synthesis and glycosidase inhibition of DAB derivatives with C-4 peptide and dipeptide branches.

Design, synthesis and glycosidase inhibition of DAB derivatives with C-4 peptide and dipeptide branches.

Journal: Organic & biomolecular chemistry

Published: March 14, 2023

Production of d-aldotetrose from l-erythrulose using various isomerases.

Production of d-aldotetrose from l-erythrulose using various isomerases.

Journal: Bioscience, biotechnology, and biochemistry

Published: February 08, 2023

Stable D-xylose ditriflate in divergent syntheses of dihydroxy prolines, pyrrolidines, tetrahydrofuran-2-carboxylic acids, and cyclic β-amino acids.

Stable D-xylose ditriflate in divergent syntheses of dihydroxy prolines, pyrrolidines, tetrahydrofuran-2-carboxylic acids, and cyclic β-amino acids.

Journal: Organic & biomolecular chemistry

Published: November 21, 2022

C-6 fluorinated casuarines as highly potent and selective amyloglucosidase inhibitors: Synthesis and structure-activity relationship study.

C-6 fluorinated casuarines as highly potent and selective amyloglucosidase inhibitors: Synthesis and structure-activity relationship study.

Journal: European journal of medicinal chemistry

Published: August 30, 2022

Nanomolar β-glucosidase and β-galactosidase inhibition by enantiomeric α-1-C-alkyl-1,4-dideoxy-1,4-imino-arabinitol derivatives.

Nanomolar β-glucosidase and β-galactosidase inhibition by enantiomeric α-1-C-alkyl-1,4-dideoxy-1,4-imino-arabinitol derivatives.

Journal: European journal of medicinal chemistry

Published: August 17, 2022

Introduction of C-alkyl branches to L-iminosugars changes their active site binding orientation.

Introduction of C-alkyl branches to L-iminosugars changes their active site binding orientation.

Journal: Organic & biomolecular chemistry

Published: July 15, 2022

Showing 1-12 of 59

Last Updated: 09/26/2026