George Lambrinidis

Athens, ESYE31 15771, Greece

Last Updated: 09/26/2026

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Found 51 publications

Recent Advances in Dual COX/LOX Inhibitor Design (2020-2024): Establishing "The Rule of Four for Inflammation".

Recent Advances in Dual COX/LOX Inhibitor Design (2020-2024): Establishing "The Rule of Four for Inflammation".

Journal: Life (Basel, Switzerland)
Published: December 12, 2025

Structural and Computational Insights into the Angiotensin II Type 1 Receptor: Advances in Antagonist Design and Implications for Hypertension Therapy (2020-2024).

Structural and Computational Insights into the Angiotensin II Type 1 Receptor: Advances in Antagonist Design and Implications for Hypertension Therapy (2020-2024).

Journal: Biomolecules
Published: November 02, 2025

Structure-Based Design of Covalent SARS-CoV‑2 Main Protease Inhibitors Targeting the Nirmatrelvir-Resistant E166 Mutants.

Structure-Based Design of Covalent SARS-CoV‑2 Main Protease Inhibitors Targeting the Nirmatrelvir-Resistant E166 Mutants.

Journal: JACS Au
Published: September 08, 2025

Identification of naturally occurring drug-resistant mutations of SARS-CoV-2 papain-like protease.

Identification of naturally occurring drug-resistant mutations of SARS-CoV-2 papain-like protease.

Journal: Nature communications
Published: December 20, 2024

Towards New Scaffolds for Antimicrobial Activity-In Silico/In Vitro Workflow Introducing New Lead Compounds.

Towards New Scaffolds for Antimicrobial Activity-In Silico/In Vitro Workflow Introducing New Lead Compounds.

Journal: Antibiotics (Basel, Switzerland)
Published: November 17, 2024

Synthesis and Preclinical Evaluation of a Bispecific PSMA-617/RM2 Heterodimer Targeting Prostate Cancer.

Synthesis and Preclinical Evaluation of a Bispecific PSMA-617/RM2 Heterodimer Targeting Prostate Cancer.

Journal: ACS medicinal chemistry letters
Published: August 11, 2024

Hit-to-Lead Optimization of Heterocyclic Carbonyloxycarboximidamides as Selective Antagonists at Human Adenosine A3 Receptor.

Hit-to-Lead Optimization of Heterocyclic Carbonyloxycarboximidamides as Selective Antagonists at Human Adenosine A3 Receptor.

Journal: Journal of medicinal chemistry
Published: July 29, 2024

A rationally designed 2C inhibitor prevents enterovirus D68-infected mice from developing paralysis.

A rationally designed 2C inhibitor prevents enterovirus D68-infected mice from developing paralysis.

Journal: Nature communications
Published: June 14, 2024

Hydrolytic Activity of Mitochondrial F1FO-ATP Synthase as a Target for Myocardial Ischemia-Reperfusion Injury: Discovery and In Vitro and In Vivo Evaluation of Novel Inhibitors.

Hydrolytic Activity of Mitochondrial F1FO-ATP Synthase as a Target for Myocardial Ischemia-Reperfusion Injury: Discovery and In Vitro and In Vivo Evaluation of Novel Inhibitors.

Journal: Journal of medicinal chemistry
Published: November 09, 2023

Structure-Based Lead Optimization of Enterovirus D68 2A Protease Inhibitors.

Structure-Based Lead Optimization of Enterovirus D68 2A Protease Inhibitors.

Journal: Journal of medicinal chemistry
Published: October 19, 2023

Synthesis and Biological Evaluation of Resveratrol Methoxy Derivatives.

Synthesis and Biological Evaluation of Resveratrol Methoxy Derivatives.

Journal: Molecules (Basel, Switzerland)
Published: June 19, 2023

Accurate calculation of affinity changes to the close state of influenza A M2 transmembrane domain in response to subtle structural changes of adamantyl amines using free energy perturbation methods in different lipid bilayers.

Accurate calculation of affinity changes to the close state of influenza A M2 transmembrane domain in response to subtle structural changes of adamantyl amines using free energy perturbation methods in different lipid bilayers.

Journal: Biochimica et biophysica acta. Biomembranes
Published: June 06, 2023
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Last Updated: 09/26/2026