George R. Douglas
Ottawa, ON, Canada
Last Updated: 09/26/2026
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Found 29 publications
An evaluation of the utility of blood concentration of somatic mutagens to inform germ cell mutagenic hazard.
Journal: Regulatory toxicology and pharmacology : RTP
Published: May 04, 2025
Temporal analyses of germ cell mutations using the MutaMouse model support the recommended design in OECD test guideline 488.
Journal: Archives of toxicology
Published: March 04, 2025
Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT).
Journal: Environmental and molecular mutagenesis
Published: December 21, 2023
Error-corrected next generation sequencing - Promises and challenges for genotoxicity and cancer risk assessment.
Journal: Mutation research. Reviews in mutation research
Published: March 09, 2023
Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing (IWGT).
Journal: Environmental and molecular mutagenesis
Published: January 17, 2023
Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing.
Journal: Nature reviews. Drug discovery
Published: January 16, 2023
Impact of sampling time on the detection of mutations in rapidly proliferating tissues using transgenic rodent gene mutation models: A review.
Journal: Environmental and molecular mutagenesis
Published: July 29, 2022
The 28 + 28 day design is an effective sampling time for analyzing mutant frequencies in rapidly proliferating tissues of MutaMouse animals.
Journal: Archives of toxicology
Published: October 13, 2020
Analysis of Biomarkers of DNA Damage and Mutagenicity in Mice Exposed to Acrylonitrile.
Journal: Chemical research in toxicology
Published: June 13, 2020
Analysis of DNA Adducts and Mutagenic Potency and Specificity in Rats Exposed to Acrylonitrile.
Journal: Chemical research in toxicology
Published: June 13, 2020
In utero Exposure to Genotoxicants Leading to Genetic Mosaicism: An Overlooked Window of Susceptibility in Genetic Toxicology Testing?
Journal: Environmental and molecular mutagenesis
Published: September 25, 2019
A Return to the Origin of the EMGS: Rejuvenating the Quest for Human Germ Cell Mutagens and Determining the Risk to Future Generations.
Journal: Environmental and molecular mutagenesis
Published: July 29, 2019
Last Updated: 09/26/2026