Last Updated: 09/26/2026
Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 7 publications
Discovery and Optimization of Biaryl Alkyl Ethers as a Novel Class of Highly Selective, CNS-Penetrable, and Orally Active Adaptor Protein-2-Associated Kinase 1 (AAK1) Inhibitors for the Potential Treatment of Neuropathic Pain.
Journal: Journal of medicinal chemistry
Published: March 09, 2022
Discovery of (S)-1-((2',6-Bis(difluoromethyl)-[2,4'-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine (BMS-986176/LX-9211): A Highly Selective, CNS Penetrable, and Orally Active Adaptor Protein-2 Associated Kinase 1 Inhibitor in Clinical Trials for the Treatment of Neuropathic Pain.
Journal: Journal of medicinal chemistry
Published: March 08, 2022
Azepino-indazoles as calcitonin gene-related peptide (CGRP) receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters
Published: July 08, 2020
Assessing seizure liability using multi-electrode arrays (MEA).
Journal: Toxicology in vitro : an international journal published in association with BIBRA
Published: July 13, 2018
Discovery of (R)-N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide (BMS-742413): a potent human CGRP antagonist with superior safety profile for the treatment of migraine through intranasal delivery.
Journal: Bioorganic & medicinal chemistry letters
Published: February 20, 2013
The synthesis and SAR of calcitonin gene-related peptide (CGRP) receptor antagonists derived from tyrosine surrogates. Part 2.
Journal: Bioorganic & medicinal chemistry letters
Published: November 02, 2012
The synthesis and SAR of calcitonin gene-related peptide (CGRP) receptor antagonists derived from tyrosine surrogates. Part 1.
Journal: Bioorganic & medicinal chemistry letters
Published: April 17, 2012
Showing 1-7 of 7
Last Updated: 09/26/2026