Georgia Gunther

Dortmund, NW 44139, Germany

Last Updated: 09/26/2026

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Found 18 publications

A simplified LC-MS-based method for sensitive analysis of DNA adducts utilizing accessible in vitro metabolism models.

A simplified LC-MS-based method for sensitive analysis of DNA adducts utilizing accessible in vitro metabolism models.

Journal: Archives of toxicology

Published: May 20, 2025

Comparative metabolism of aflatoxin B1 in mouse, rat and human primary hepatocytes using HPLC-MS/MS.

Comparative metabolism of aflatoxin B1 in mouse, rat and human primary hepatocytes using HPLC-MS/MS.

Journal: Archives of toxicology

Published: July 03, 2023

The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds.

The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds.

Journal: Chemico-biological interactions

Published: June 23, 2021

Pyrrolizidine alkaloid-induced transcriptomic changes in rat lungs in a 28-day subacute feeding study.

Pyrrolizidine alkaloid-induced transcriptomic changes in rat lungs in a 28-day subacute feeding study.

Journal: Archives of toxicology

Published: April 21, 2021

Intravital Dynamic and Correlative Imaging of Mouse Livers Reveals Diffusion-Dominated Canalicular and Flow-Augmented Ductular Bile Flux.

Intravital Dynamic and Correlative Imaging of Mouse Livers Reveals Diffusion-Dominated Canalicular and Flow-Augmented Ductular Bile Flux.

Journal: Hepatology (Baltimore, Md.)

Published: February 09, 2020

Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S.

Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S.

Journal: Chemical science

Published: July 12, 2019

The pyrrolizidine alkaloid senecionine induces CYP-dependent destruction of sinusoidal endothelial cells and cholestasis in mice.

The pyrrolizidine alkaloid senecionine induces CYP-dependent destruction of sinusoidal endothelial cells and cholestasis in mice.

Journal: Archives of toxicology

Published: July 01, 2019

Pipe-3D: A Pipeline Based on Immunofluorescence, 3D Confocal Imaging, Reconstructions, and Morphometry for Biliary Network Analysis in Cholestasis.

Pipe-3D: A Pipeline Based on Immunofluorescence, 3D Confocal Imaging, Reconstructions, and Morphometry for Biliary Network Analysis in Cholestasis.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: April 25, 2019

Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in KRAS-Mutant Pancreatic and Colorectal Cancer.

Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in KRAS-Mutant Pancreatic and Colorectal Cancer.

Journal: Cancer research

Published: September 11, 2018

Pyrrolizidine alkaloid-induced alterations of prostanoid synthesis in human endothelial cells.

Pyrrolizidine alkaloid-induced alterations of prostanoid synthesis in human endothelial cells.

Journal: Chemico-biological interactions

Published: August 16, 2018

Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood.

Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood.

Journal: Hepatology (Baltimore, Md.)

Published: October 21, 2017

Structure-Guided Development of Covalent and Mutant-Selective Pyrazolopyrimidines to Target T790M Drug Resistance in Epidermal Growth Factor Receptor.

Structure-Guided Development of Covalent and Mutant-Selective Pyrazolopyrimidines to Target T790M Drug Resistance in Epidermal Growth Factor Receptor.

Journal: Journal of medicinal chemistry

Published: August 31, 2017

Showing 1-12 of 18

Last Updated: 09/26/2026