Last Updated: 09/26/2026
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Found 3 publications
Localization of TCR-expressing natural intraepithelial lymphocytes in the colon epithelium depends on GPR15 and epithelium-derived C10ORF99.
Journal: Mucosal immunology
Published: December 31, 2025
C10ORF99 (GPR15L) increases susceptibility to colitis and colitis-induced colorectal cancer via GPR15-independent mechanisms, while mediating GPR15-dependent T cell migration to the large intestine.
Journal: Mucosal immunology
Published: April 28, 2025
Dietary L-Tryptophan consumption determines the number of colonic regulatory T cells and susceptibility to colitis via GPR15.
Journal: Nature communications
Published: January 18, 2023
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Last Updated: 09/26/2026