Gerald T. Nepom

Medical Genetics
1201 9th Ave
Seattle, WA 98101

Last Updated: 09/26/2026

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Found 64 publications

Corrigendum to: Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes.

Corrigendum to: Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes.

Journal: JCI insight
Published: April 22, 2026

Genetic Determinants of Peanut-Specific IgG4 Levels in the Context of Sustained Oral Peanut Exposure in the LEAP Study.

Genetic Determinants of Peanut-Specific IgG4 Levels in the Context of Sustained Oral Peanut Exposure in the LEAP Study.

Journal: Immunology
Published: September 15, 2025

Early expansion of TIGIT+PD1+ effector memory CD4 T cells via agonistic effect of alefacept in new-onset type 1 diabetes.

Early expansion of TIGIT+PD1+ effector memory CD4 T cells via agonistic effect of alefacept in new-onset type 1 diabetes.

Journal: Journal of immunology (Baltimore, Md. : 1950)
Published: September 16, 2024

Donor-specific immune senescence as a candidate biomarker of operational tolerance following liver transplantation in adults: Results of a prospective, multicenter cohort study.

Donor-specific immune senescence as a candidate biomarker of operational tolerance following liver transplantation in adults: Results of a prospective, multicenter cohort study.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Published: May 10, 2024

Breakdown and Repair of Peripheral Immune Tolerance in Type 1 Diabetes.

Breakdown and Repair of Peripheral Immune Tolerance in Type 1 Diabetes.

Journal: Cold Spring Harbor perspectives in medicine
Published: May 01, 2024

Evolving Concepts in Pathophysiology, Screening, and Prevention of Type 1 Diabetes: Report of Diabetes Mellitus Interagency Coordinating Committee Workshop.

Evolving Concepts in Pathophysiology, Screening, and Prevention of Type 1 Diabetes: Report of Diabetes Mellitus Interagency Coordinating Committee Workshop.

Journal: Diabetes
Published: May 01, 2024

Interconnected lineage trajectories link conventional and natural killer (NK)-like exhausted CD8+ T cells beneficial in type 1 diabetes.

Interconnected lineage trajectories link conventional and natural killer (NK)-like exhausted CD8+ T cells beneficial in type 1 diabetes.

Journal: Communications biology
Published: August 17, 2023

A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab.

A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab.

Journal: Diabetologia
Published: May 24, 2023

FOXP3+ regulatory T cells use heparanase to access IL-2 bound to ECM in inflamed tissues.

FOXP3+ regulatory T cells use heparanase to access IL-2 bound to ECM in inflamed tissues.

Journal: bioRxiv : the preprint server for biology
Published: March 13, 2023

Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue.

Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue.

Journal: Nature communications
Published: February 22, 2023

Islet-autoreactive CD4+ T cells are linked with response to alefacept in type 1 diabetes.

Islet-autoreactive CD4+ T cells are linked with response to alefacept in type 1 diabetes.

Journal: JCI insight
Published: December 08, 2022

Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy.

Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy.

Journal: The Journal of allergy and clinical immunology
Published: July 28, 2022
Showing 1-12 of 64

Last Updated: 09/26/2026