Gerd Multhaup

Montreal, QC H3G1Y6, Canada

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 24 publications

Mechanisms of amyloid-β34 generation indicate a pivotal role for BACE1 in amyloid homeostasis.

Mechanisms of amyloid-β34 generation indicate a pivotal role for BACE1 in amyloid homeostasis.

Journal: Scientific reports

Published: November 10, 2022

Understanding the Interaction of Polyelectrolyte Architectures with Proteins and Biosystems.

Understanding the Interaction of Polyelectrolyte Architectures with Proteins and Biosystems.

Journal: Angewandte Chemie (International ed. in English)

Published: May 04, 2020

Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer's disease progression.

Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer's disease progression.

Journal: Nature communications

Published: May 01, 2018

Hyperbranched Polyglycerol Derivatives as Prospective Copper Nanotransporter Candidates.

Hyperbranched Polyglycerol Derivatives as Prospective Copper Nanotransporter Candidates.

Journal: Molecules (Basel, Switzerland)

Published: March 28, 2018

Dimerization of the cellular prion protein inhibits propagation of scrapie prions.

Dimerization of the cellular prion protein inhibits propagation of scrapie prions.

Journal: The Journal of biological chemistry

Published: November 16, 2017

APLP1 is endoproteolytically cleaved by γ-secretase without previous ectodomain shedding.

APLP1 is endoproteolytically cleaved by γ-secretase without previous ectodomain shedding.

Journal: Scientific reports

Published: June 30, 2017

Full-length cellular β-secretase has a trimeric subunit stoichiometry, and its sulfur-rich transmembrane interaction site modulates cytosolic copper compartmentalization.

Full-length cellular β-secretase has a trimeric subunit stoichiometry, and its sulfur-rich transmembrane interaction site modulates cytosolic copper compartmentalization.

Journal: The Journal of biological chemistry

Published: January 31, 2017

Sulindac Sulfide Induces the Formation of Large Oligomeric Aggregates of the Alzheimer's Disease Amyloid-β Peptide Which Exhibit Reduced Neurotoxicity.

Sulindac Sulfide Induces the Formation of Large Oligomeric Aggregates of the Alzheimer's Disease Amyloid-β Peptide Which Exhibit Reduced Neurotoxicity.

Journal: Biochemistry

Published: February 23, 2016

Amyloid Precursor Protein (APP) Metabolites APP Intracellular Fragment (AICD), Aβ42, and Tau in Nuclear Roles.

Amyloid Precursor Protein (APP) Metabolites APP Intracellular Fragment (AICD), Aβ42, and Tau in Nuclear Roles.

Journal: The Journal of biological chemistry

Published: August 23, 2015

Structural Mechanism of the Interaction of Alzheimer Disease Aβ Fibrils with the Non-steroidal Anti-inflammatory Drug (NSAID) Sulindac Sulfide.

Structural Mechanism of the Interaction of Alzheimer Disease Aβ Fibrils with the Non-steroidal Anti-inflammatory Drug (NSAID) Sulindac Sulfide.

Journal: The Journal of biological chemistry

Published: June 27, 2015

Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes.

Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes.

Journal: Acta crystallographica. Section D, Biological crystallography

Published: October 01, 2014

Nuclear translocation uncovers the amyloid peptide Aβ42 as a regulator of gene transcription.

Nuclear translocation uncovers the amyloid peptide Aβ42 as a regulator of gene transcription.

Journal: The Journal of biological chemistry

Published: June 01, 2014

Showing 1-12 of 24

Last Updated: 09/26/2026