Gergely L. Lukacs

Montreal, QC H3G1Y6, Canada

Last Updated: 09/26/2026

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Found 76 publications

Triple potentiator combinations increase the functional correction of several CFTR gating mutants.

Triple potentiator combinations increase the functional correction of several CFTR gating mutants.

Journal: npj drug discovery

Published: November 21, 2025

Substrate recognition by the human mitochondrial processing peptidase and its processing of PINK1.

Substrate recognition by the human mitochondrial processing peptidase and its processing of PINK1.

Journal: The Journal of biological chemistry

Published: April 07, 2025

Synthesis and Biological Evaluation of Pyrazole-Pyrimidones as a New Class of Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).

Synthesis and Biological Evaluation of Pyrazole-Pyrimidones as a New Class of Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).

Journal: Journal of medicinal chemistry

Published: August 13, 2024

SARS-CoV-2 envelope protein alters calcium signaling via SERCA interactions.

SARS-CoV-2 envelope protein alters calcium signaling via SERCA interactions.

Journal: Scientific reports

Published: March 06, 2024

Readthrough-induced misincorporated amino acid ratios guide mutant-specific therapeutic approaches for two CFTR nonsense mutations.

Readthrough-induced misincorporated amino acid ratios guide mutant-specific therapeutic approaches for two CFTR nonsense mutations.

Journal: Frontiers in pharmacology

Published: February 21, 2024

Analysis of AlphaMissense data in different protein groups and structural context.

Analysis of AlphaMissense data in different protein groups and structural context.

Journal: Scientific data

Published: December 04, 2023

Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling.

Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling.

Journal: bioRxiv : the preprint server for biology

Published: October 31, 2023

HERC3 facilitates ERAD of select membrane proteins by recognizing membrane-spanning domains.

HERC3 facilitates ERAD of select membrane proteins by recognizing membrane-spanning domains.

Journal: The Journal of cell biology

Published: August 01, 2023

Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling.

Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling.

Journal: Nature communications

Published: November 16, 2022

Design of Crotoxin-Based Peptides with Potentiator Activity Targeting the ΔF508NBD1 Cystic Fibrosis Transmembrane Conductance Regulator.

Design of Crotoxin-Based Peptides with Potentiator Activity Targeting the ΔF508NBD1 Cystic Fibrosis Transmembrane Conductance Regulator.

Journal: Journal of molecular biology

Published: September 29, 2022

Measuring EGFR plasma membrane density, stability, internalization, and recycling in alive adherent cells by cell surface ELISA.

Measuring EGFR plasma membrane density, stability, internalization, and recycling in alive adherent cells by cell surface ELISA.

Journal: STAR protocols

Published: June 27, 2022

A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases.

A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases.

Journal: Science translational medicine

Published: March 30, 2022

Showing 1-12 of 76

Last Updated: 09/26/2026