Gerhard Purstinger
Innsbruck, 6020, Austria
Last Updated: 09/26/2026
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Found 14 publications
Design, synthesis, and lead optimization of piperazinyl-pyrimidine analogues as potent small molecules targeting the viral capping machinery of Chikungunya virus.
Journal: European journal of medicinal chemistry
Published: September 12, 2023
Structural Insights into the Mechanisms of Action of Functionally Distinct Classes of Chikungunya Virus Nonstructural Protein 1 Inhibitors.
Journal: Antimicrobial agents and chemotherapy
Published: April 20, 2021
Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery.
Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery.
Journal: Antimicrobial agents and chemotherapy
Published: April 03, 2020
Quinolinecarboxamides Inhibit the Replication of the Bovine Viral Diarrhea Virus by Targeting a Hot Spot for the Inhibition of Pestivirus Replication in the RNA-Dependent RNA Polymerase.
Journal: Molecules (Basel, Switzerland)
Published: January 31, 2020
Identification of 2-(4-(Phenylsulfonyl)piperazine-1-yl)pyrimidine Analogues as Novel Inhibitors of Chikungunya Virus.
Journal: ACS medicinal chemistry letters
Published: December 30, 2019
Allosteric Regulation of Phosphatidylinositol 4-Kinase III Beta by an Antipicornavirus Compound MDL-860.
Journal: ACS infectious diseases
Published: June 13, 2017
Anti-enteroviral triple combination of viral replication inhibitors: activity against coxsackievirus B1 neuroinfection in mice.
Journal: Antiviral chemistry & chemotherapy
Published: November 06, 2016
Structure Elucidation of Coxsackievirus A16 in Complex with GPP3 Informs a Systematic Review of Highly Potent Capsid Binders to Enteroviruses.
Journal: PLoS pathogens
Published: May 31, 2015
The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.
Journal: PLoS pathogens
Published: October 05, 2014
H1PVAT is a novel and potent early-stage inhibitor of poliovirus replication that targets VP1.
Journal: Antiviral research
Published: April 07, 2014
Synthesis, cytotoxic, and antitumor activities of 2-pyridylhydrazones derived from 3-benzoylpyridazines.
Journal: Archiv der Pharmazie
Published: April 07, 2014
More-powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules.
Journal: Nature structural & molecular biology
Published: July 02, 2013
Last Updated: 09/26/2026