Gian P. Camenisch

Basel, BS, Switzerland

Last Updated: 09/26/2026

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Found 33 publications

Drug-induced cholestasis (DIC) predictions based on in vitro inhibition of major bile acid clearance mechanisms.

Drug-induced cholestasis (DIC) predictions based on in vitro inhibition of major bile acid clearance mechanisms.

Journal: Archives of toxicology

Published: September 28, 2023

Identification of reversible OATP1B1 and time-dependent CYP3A4 inhibition as the major risk factors for drug-induced cholestasis (DIC).

Identification of reversible OATP1B1 and time-dependent CYP3A4 inhibition as the major risk factors for drug-induced cholestasis (DIC).

Journal: Archives of toxicology

Published: September 28, 2023

Novel insights into bile acid detoxification via CYP, UGT and SULT enzymes.

Novel insights into bile acid detoxification via CYP, UGT and SULT enzymes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA

Published: June 29, 2022

Evaluation of the Absorption, Metabolism, and Excretion of a Single Oral 1-mg Dose of Tropifexor in Healthy Male Subjects and the Concentration Dependence of Tropifexor Metabolism.

Evaluation of the Absorption, Metabolism, and Excretion of a Single Oral 1-mg Dose of Tropifexor in Healthy Male Subjects and the Concentration Dependence of Tropifexor Metabolism.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: December 29, 2020

Double Trap Interface: A novel gas interface for high throughput analysis of biomedical samples by AMS.

Double Trap Interface: A novel gas interface for high throughput analysis of biomedical samples by AMS.

Journal: Drug metabolism and pharmacokinetics

Published: December 14, 2020

An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data.

An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data.

Journal: Pharmacology research & perspectives

Published: April 22, 2020

Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite.

Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: February 25, 2020

Fevipiprant has a low risk of influencing co-medication pharmacokinetics: Impact on simvastatin and rosuvastatin in different SLCO1B1 genotypes.

Fevipiprant has a low risk of influencing co-medication pharmacokinetics: Impact on simvastatin and rosuvastatin in different SLCO1B1 genotypes.

Journal: Pulmonary pharmacology & therapeutics

Published: November 28, 2018

Examining P-gp efflux kinetics guided by the BDDCS - Rational selection of in vitro assay designs and mathematical models.

Examining P-gp efflux kinetics guided by the BDDCS - Rational selection of in vitro assay designs and mathematical models.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: November 23, 2018

Comparison of Rat and Human Pulmonary Metabolism Using Precision-cut Lung Slices (PCLS).

Comparison of Rat and Human Pulmonary Metabolism Using Precision-cut Lung Slices (PCLS).

Journal: Drug metabolism letters

Published: August 03, 2018

Models and Approaches Describing the Metabolism, Transport, and Toxicity of Drugs Administered by the Ocular Route.

Models and Approaches Describing the Metabolism, Transport, and Toxicity of Drugs Administered by the Ocular Route.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: June 11, 2018

Functional assessment of rat pulmonary flavin-containing monooxygenase activity.

Functional assessment of rat pulmonary flavin-containing monooxygenase activity.

Journal: Xenobiotica; the fate of foreign compounds in biological systems

Published: April 26, 2018

Showing 1-12 of 33

Last Updated: 09/26/2026