Gill Holdsworth

Slough, ENG SL13WE, United Kingdom

Last Updated: 09/26/2026

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Found 25 publications

Characterising skull pathologies in the Sost-deficient mouse for preclinical evaluation of sclerosteosis treatments.

Characterising skull pathologies in the Sost-deficient mouse for preclinical evaluation of sclerosteosis treatments.

Journal: Disease models & mechanisms

Published: January 23, 2026

Early intermittent low-dose sclerostin antibody treatment promotes surface bone formation and reduces bone loss, but also decreases osteocyte apoptosis and mechanotransduction in ovariectomized rats: A pilot study.

Early intermittent low-dose sclerostin antibody treatment promotes surface bone formation and reduces bone loss, but also decreases osteocyte apoptosis and mechanotransduction in ovariectomized rats: A pilot study.

Journal: Bone reports

Published: December 19, 2025

Extracellular pH is a critical regulator of osteoclast fusion, size and activation.

Extracellular pH is a critical regulator of osteoclast fusion, size and activation.

Journal: Bone

Published: November 22, 2024

Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies.

Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies.

Journal: Bone research

Published: May 31, 2024

Genetic data do not provide evidence that lower sclerostin is associated with increased risk of atherosclerosis: comment on the article by Zheng et al.

Genetic data do not provide evidence that lower sclerostin is associated with increased risk of atherosclerosis: comment on the article by Zheng et al.

Journal: Arthritis & rheumatology (Hoboken, N.J.)

Published: September 19, 2023

A Machine Learning-Based Image Segmentation Method to Quantify In Vitro Osteoclast Culture Endpoints.

A Machine Learning-Based Image Segmentation Method to Quantify In Vitro Osteoclast Culture Endpoints.

Journal: Calcified tissue international

Published: June 06, 2023

A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise.

A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise.

Journal: Cell stem cell

Published: June 12, 2021

Recombinant sclerostin inhibits bone formation in vitro and in a mouse model of sclerosteosis.

Recombinant sclerostin inhibits bone formation in vitro and in a mouse model of sclerosteosis.

Journal: Journal of orthopaedic translation

Published: March 08, 2021

Osteocyte mechanosensing following short-term and long-term treatment with sclerostin antibody.

Osteocyte mechanosensing following short-term and long-term treatment with sclerostin antibody.

Journal: Bone

Published: January 25, 2021

Sclerostin Downregulation Globally by Naturally Occurring Genetic Variants, or Locally in Atherosclerotic Plaques, Does Not Associate With Cardiovascular Events in Humans.

Sclerostin Downregulation Globally by Naturally Occurring Genetic Variants, or Locally in Atherosclerotic Plaques, Does Not Associate With Cardiovascular Events in Humans.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Published: December 02, 2020

Sclerostin antibody increases trabecular bone and bone mechanical properties by increasing osteoblast activity damaged by whole-body irradiation in mice.

Sclerostin antibody increases trabecular bone and bone mechanical properties by increasing osteoblast activity damaged by whole-body irradiation in mice.

Journal: Bone

Published: November 10, 2020

Scl-Ab reverts pro-osteoclastogenic signalling and resorption in estrogen deficient osteocytes.

Scl-Ab reverts pro-osteoclastogenic signalling and resorption in estrogen deficient osteocytes.

Journal: BMC molecular and cell biology

Published: August 18, 2020

Showing 1-12 of 25

Last Updated: 09/26/2026