Gisele M. Barbosa

Rio De Janeiro, RJ, Brazil

Last Updated: 09/26/2026

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Found 13 publications

Investigation on LASSBio-1971 and LASSBio-1974 Cellular Cytotoxic Mechanism and Their Comparative DMPK Profile.

Investigation on LASSBio-1971 and LASSBio-1974 Cellular Cytotoxic Mechanism and Their Comparative DMPK Profile.

Journal: Archiv der Pharmazie

Published: July 28, 2025

Hit-to-Lead Studies of Pyrazinylpiperazines against Visceral Leishmaniasis: Pharmacokinetic Profile and In Vivo Efficacy of Potent Compounds against Leishmania infantum.

Hit-to-Lead Studies of Pyrazinylpiperazines against Visceral Leishmaniasis: Pharmacokinetic Profile and In Vivo Efficacy of Potent Compounds against Leishmania infantum.

Journal: ACS pharmacology & translational science

Published: April 29, 2025

Evaluation of pretreatment routes for seawater desalination by nanofiltration.

Evaluation of pretreatment routes for seawater desalination by nanofiltration.

Journal: Water science and technology : a journal of the International Association on Water Pollution Research

Published: September 02, 2024

Cytotoxic and Antiproliferative Activity of LASSBio-2208 and the Attempts to Determine Its Drug Metabolism and Pharmacokinetics In Vitro Profile.

Cytotoxic and Antiproliferative Activity of LASSBio-2208 and the Attempts to Determine Its Drug Metabolism and Pharmacokinetics In Vitro Profile.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: February 13, 2024

Design, Synthesis and Phenotypic Profiling of Simplified Gedatolisib Analogues.

Design, Synthesis and Phenotypic Profiling of Simplified Gedatolisib Analogues.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: December 30, 2022

2-Arylpropionic Acid Pyrazolamides as Cannabinoid CB2 Receptor Inverse Agonists Endowed with Anti-Inflammatory Properties.

2-Arylpropionic Acid Pyrazolamides as Cannabinoid CB2 Receptor Inverse Agonists Endowed with Anti-Inflammatory Properties.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: October 02, 2022

Discovery of Putative Dual Inhibitor of Tubulin and EGFR by Phenotypic Approach on LASSBio-1586 Homologs.

Discovery of Putative Dual Inhibitor of Tubulin and EGFR by Phenotypic Approach on LASSBio-1586 Homologs.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: June 29, 2022

Pre-clinical evaluation of LASSBio-1491: From in vitro pharmacokinetic study to in vivo leishmanicidal activity.

Pre-clinical evaluation of LASSBio-1491: From in vitro pharmacokinetic study to in vivo leishmanicidal activity.

Journal: PloS one

Published: January 21, 2022

Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation.

Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation.

Journal: RSC medicinal chemistry

Published: November 22, 2021

β-lactam antibiotics: An overview from a medicinal chemistry perspective.

β-lactam antibiotics: An overview from a medicinal chemistry perspective.

Journal: European journal of medicinal chemistry

Published: August 07, 2020

The terpenic diamine GIB24 inhibits the growth of Trypanosoma cruzi epimastigotes and intracellular amastigotes, with proteomic analysis of drug-resistant epimastigotes.

The terpenic diamine GIB24 inhibits the growth of Trypanosoma cruzi epimastigotes and intracellular amastigotes, with proteomic analysis of drug-resistant epimastigotes.

Journal: Chemico-biological interactions

Published: April 10, 2020

Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies.

Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies.

Journal: European journal of medicinal chemistry

Published: March 18, 2020

Showing 1-12 of 13

Last Updated: 09/26/2026