Giulia Guarguaglini

Rome, Italy

Last Updated: 09/26/2026

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Found 32 publications

The ATC12 small molecule inhibits the Aurora-A/TPX2 interaction and impairs the proliferation of breast cancer cells.

The ATC12 small molecule inhibits the Aurora-A/TPX2 interaction and impairs the proliferation of breast cancer cells.

Journal: Cell death & disease

Published: July 17, 2025

RNA-mediated inhibition of mitochondrial SHMT2 impairs cancer cell proliferation.

RNA-mediated inhibition of mitochondrial SHMT2 impairs cancer cell proliferation.

Journal: Cell death discovery

Published: March 03, 2025

Unraveling the Engagement of Kinases to CRBN Through a Shared Structural Motif to Optimize PROTACs Efficacy.

Unraveling the Engagement of Kinases to CRBN Through a Shared Structural Motif to Optimize PROTACs Efficacy.

Journal: Biomolecules

Published: December 31, 2024

Contribution of AurkA/TPX2 Overexpression to Chromosomal Imbalances and Cancer.

Contribution of AurkA/TPX2 Overexpression to Chromosomal Imbalances and Cancer.

Journal: Cells

Published: July 12, 2024

AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway.

AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway.

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: September 08, 2023

M2 muscarinic receptors negatively modulate cell migration in human glioblastoma cells.

M2 muscarinic receptors negatively modulate cell migration in human glioblastoma cells.

Journal: Neurochemistry international

Published: September 08, 2023

ALFI: Cell cycle phenotype annotations of label-free time-lapse imaging data from cultured human cells.

ALFI: Cell cycle phenotype annotations of label-free time-lapse imaging data from cultured human cells.

Journal: Scientific data

Published: February 21, 2023

When Just One Phosphate Is One Too Many: The Multifaceted Interplay between Myc and Kinases.

When Just One Phosphate Is One Too Many: The Multifaceted Interplay between Myc and Kinases.

Journal: International journal of molecular sciences

Published: January 24, 2023

AMBRA1 phosphorylation by CDK1 and PLK1 regulates mitotic spindle orientation.

AMBRA1 phosphorylation by CDK1 and PLK1 regulates mitotic spindle orientation.

Journal: Cellular and molecular life sciences : CMLS

Published: December 31, 2022

AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation.

AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation.

Journal: Life science alliance

Published: September 16, 2022

Revisiting degron motifs in human AURKA required for its targeting by APC/CFZR1.

Revisiting degron motifs in human AURKA required for its targeting by APC/CFZR1.

Journal: Life science alliance

Published: January 16, 2022

PHA-680626 Is an Effective Inhibitor of the Interaction between Aurora-A and N-Myc.

PHA-680626 Is an Effective Inhibitor of the Interaction between Aurora-A and N-Myc.

Journal: International journal of molecular sciences

Published: October 20, 2021

Showing 1-12 of 32

Last Updated: 09/26/2026