Giuseppe Manfroni

Via Del Liceo 1
Perugia, 06123, Italy

Last Updated: 09/26/2026

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Found 74 publications

SARgate: a structure-bioactivity analyser for navigating chemical space and mining SAR trends.

SARgate: a structure-bioactivity analyser for navigating chemical space and mining SAR trends.

Journal: European journal of medicinal chemistry

Published: May 16, 2026

Streamlined Synthesis and Structure-Activity Relationship Analysis of 2-Amidothiophene-3-Carboxamides Targeting Influenza Polymerase PA-PB1 Heterodimerization.

Streamlined Synthesis and Structure-Activity Relationship Analysis of 2-Amidothiophene-3-Carboxamides Targeting Influenza Polymerase PA-PB1 Heterodimerization.

Journal: ChemMedChem

Published: March 30, 2026

Sulfonyl Anthranilic Acid Analogues Display Pan-Serotype Anti-Dengue Activity by Downregulating the Expression of Ribosomal Proteins Encoded by 5'-Terminal Oligopyrimidine Motif-Containing mRNA.

Sulfonyl Anthranilic Acid Analogues Display Pan-Serotype Anti-Dengue Activity by Downregulating the Expression of Ribosomal Proteins Encoded by 5'-Terminal Oligopyrimidine Motif-Containing mRNA.

Journal: Journal of medicinal chemistry

Published: March 10, 2026

2-Phenylquinolines Exhibit Anti-Severe Acute Respiratory Syndrome Coronavirus-2 Activity Through the Nonstructural Protein 13 Helicase Inhibition.

2-Phenylquinolines Exhibit Anti-Severe Acute Respiratory Syndrome Coronavirus-2 Activity Through the Nonstructural Protein 13 Helicase Inhibition.

Journal: ChemMedChem

Published: November 21, 2025

Optimization of 2,3-dihydrophthalazine-1,4-dione PARP inhibitor scaffold for nanomolar potency and specificity towards human PARP10.

Optimization of 2,3-dihydrophthalazine-1,4-dione PARP inhibitor scaffold for nanomolar potency and specificity towards human PARP10.

Journal: European journal of medicinal chemistry

Published: July 02, 2025

A medicinal chemistry overview of direct-acting antivirals approved in 2013-2024 by US FDA.

A medicinal chemistry overview of direct-acting antivirals approved in 2013-2024 by US FDA.

Journal: European journal of medicinal chemistry

Published: June 17, 2025

Broad-Spectrum Antiviral Activity of Pyridobenzothiazolone Analogues Against Respiratory Viruses.

Broad-Spectrum Antiviral Activity of Pyridobenzothiazolone Analogues Against Respiratory Viruses.

Journal: Viruses

Published: April 23, 2025

New Pyridobenothiazolone Derivatives Display Nanomolar Pan-Serotype Anti-Dengue Virus Activity.

New Pyridobenothiazolone Derivatives Display Nanomolar Pan-Serotype Anti-Dengue Virus Activity.

Journal: ChemMedChem

Published: February 27, 2025

NorA Efflux Pump Inhibitors: Expanding SAR Knowledge of Pyrazolo[4,3-c][1,2]benzothiazine 5,5-Dioxide Derivatives.

NorA Efflux Pump Inhibitors: Expanding SAR Knowledge of Pyrazolo[4,3-c][1,2]benzothiazine 5,5-Dioxide Derivatives.

Journal: Archiv der Pharmazie

Published: December 12, 2024

Addressing Data Point Homogeneity and Annotation Challenges to Enhance Data-Driven Approaches: The S. aureus NorA Efflux Pump Case Study.

Addressing Data Point Homogeneity and Annotation Challenges to Enhance Data-Driven Approaches: The S. aureus NorA Efflux Pump Case Study.

Journal: ChemMedChem

Published: November 16, 2024

New anti-ovarian cancer quinolone derivatives acting by modulating microRNA processing machinery.

New anti-ovarian cancer quinolone derivatives acting by modulating microRNA processing machinery.

Journal: RSC medicinal chemistry

Published: August 22, 2024

Recent Progress toward the Discovery of Small Molecules as Novel Anti-Respiratory Syncytial Virus Agents.

Recent Progress toward the Discovery of Small Molecules as Novel Anti-Respiratory Syncytial Virus Agents.

Journal: Journal of medicinal chemistry

Published: July 06, 2024

Showing 1-12 of 74

Last Updated: 09/26/2026