Giuseppe Melacini

Hamilton, ON, Canada

Last Updated: 09/26/2026

Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 83 publications

Aortic disease-linked mutations reveal unexpected convergent allosteric mechanisms of protein kinase G misregulation.

Aortic disease-linked mutations reveal unexpected convergent allosteric mechanisms of protein kinase G misregulation.

Journal: Science advances
Published: September 02, 2026

In situ NMR and integrative proteomics reveal the interaction signature of serum α-synuclein.

In situ NMR and integrative proteomics reveal the interaction signature of serum α-synuclein.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: January 28, 2026

Activating PRKG1 Variant Enhances Smooth Muscle Cell Deformability to Cause Aortopathy.

Activating PRKG1 Variant Enhances Smooth Muscle Cell Deformability to Cause Aortopathy.

Journal: JACC. Basic to translational science
Published: August 23, 2025

Resonance assignments of asymmetric tetrameric platelet factor 4 (PF4).

Resonance assignments of asymmetric tetrameric platelet factor 4 (PF4).

Journal: Biomolecular NMR assignments
Published: June 26, 2025

Recurrent Acrodysostosis-Related PKA RIα Mutant Reveals a Novel Mechanism of Aberrant PKA Deactivation.

Recurrent Acrodysostosis-Related PKA RIα Mutant Reveals a Novel Mechanism of Aberrant PKA Deactivation.

Journal: Journal of molecular biology
Published: June 11, 2025

Unbiased clustering of residues undergoing synchronous motions in proteins using NMR spin relaxation data.

Unbiased clustering of residues undergoing synchronous motions in proteins using NMR spin relaxation data.

Journal: Biophysical chemistry
Published: October 22, 2024

Amyloid-Driven Allostery.

Amyloid-Driven Allostery.

Journal: Biophysical chemistry
Published: July 18, 2024

Probing ligand selectivity in pathogens.

Probing ligand selectivity in pathogens.

Journal: eLife
Published: December 21, 2023

Inhibition of toxic metal-alpha synuclein interactions by human serum albumin.

Inhibition of toxic metal-alpha synuclein interactions by human serum albumin.

Journal: Chemical science
Published: November 24, 2023

Early-Onset Parkinson Mutation Remodels Monomer-Fibril Interactions to Allosterically Amplify Synuclein's Amyloid Cascade.

Early-Onset Parkinson Mutation Remodels Monomer-Fibril Interactions to Allosterically Amplify Synuclein's Amyloid Cascade.

Journal: JACS Au
Published: October 26, 2023

Toward a molecular mechanism for the interaction of ATP with alpha-synuclein.

Toward a molecular mechanism for the interaction of ATP with alpha-synuclein.

Journal: Chemical science
Published: July 13, 2023

Fractionation factors reveal hidden frustration in an ancient allosteric module.

Fractionation factors reveal hidden frustration in an ancient allosteric module.

Journal: The Journal of chemical physics
Published: April 01, 2023
Showing 1-12 of 83

Last Updated: 09/26/2026