Giuseppina Arico

Catania, 95125, Italy

Last Updated: 09/26/2026

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Found 21 publications

Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT1A receptor agonists for CNS disorders and neuropathic pain.

Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT1A receptor agonists for CNS disorders and neuropathic pain.

Journal: Future medicinal chemistry

Published: July 26, 2018

Structure-Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma.

Structure-Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma.

Journal: ChemMedChem

Published: July 26, 2017

Development of novel LP1-based analogues with enhanced delta opioid receptor profile.

Development of novel LP1-based analogues with enhanced delta opioid receptor profile.

Journal: Bioorganic & medicinal chemistry

Published: May 25, 2017

(+)-Pentazocine attenuates SH-SY5Y cell death, oxidative stress and microglial migration induced by conditioned medium from activated microglia.

(+)-Pentazocine attenuates SH-SY5Y cell death, oxidative stress and microglial migration induced by conditioned medium from activated microglia.

Journal: Neuroscience letters

Published: November 29, 2016

Repeated activation of delta opiod receptors counteracts nerve injury-induced TNF-α up-regulation in the sciatic nerve of rats with neuropathic pain: A possible correlation with delta opiod receptors-mediated antiallodinic effect.

Repeated activation of delta opiod receptors counteracts nerve injury-induced TNF-α up-regulation in the sciatic nerve of rats with neuropathic pain: A possible correlation with delta opiod receptors-mediated antiallodinic effect.

Journal: Molecular pain

Published: September 04, 2016

Multitarget Opioid/Non-opioid Ligands: A Potential Approach in Pain Management.

Multitarget Opioid/Non-opioid Ligands: A Potential Approach in Pain Management.

Journal: Current medicinal chemistry

Published: June 29, 2016

Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists.

Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists.

Journal: European journal of medicinal chemistry

Published: June 12, 2016

An LP1 analogue, selective MOR agonist with a peculiar pharmacological profile, used to scrutiny the ligand binding domain.

An LP1 analogue, selective MOR agonist with a peculiar pharmacological profile, used to scrutiny the ligand binding domain.

Journal: Bioorganic & medicinal chemistry

Published: May 19, 2016

Caspase-3 activation in human melanoma A375 cell line by a novel selective sigma-2 agonist.

Caspase-3 activation in human melanoma A375 cell line by a novel selective sigma-2 agonist.

Journal: Die Pharmazie

Published: May 18, 2016

Evaluation of N-substituent structural variations in opioid receptor profile of LP1.

Evaluation of N-substituent structural variations in opioid receptor profile of LP1.

Journal: Bioorganic & medicinal chemistry

Published: April 12, 2016

Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives.

Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives.

Journal: European journal of medicinal chemistry

Published: October 01, 2015

Harpagophytum procumbens extract potentiates morphine antinociception in neuropathic rats.

Harpagophytum procumbens extract potentiates morphine antinociception in neuropathic rats.

Journal: Natural product research

Published: July 21, 2015

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Last Updated: 09/26/2026