Giuseppina Di Stefano

Bologna, 40126, Italy

Last Updated: 09/26/2026

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Found 32 publications

A Metabolites' Interplay Can Modulate DNA Repair by Homologous Recombination.

A Metabolites' Interplay Can Modulate DNA Repair by Homologous Recombination.

Journal: International journal of molecular sciences

Published: December 18, 2025

Targeting RAD51-BRCA2 Interaction to Enhance Synthetic Lethality with Olaparib in Pancreatic Cancer: Development of a Novel Phenyl Furan-Quinoline-Carboxylic Acid Series.

Targeting RAD51-BRCA2 Interaction to Enhance Synthetic Lethality with Olaparib in Pancreatic Cancer: Development of a Novel Phenyl Furan-Quinoline-Carboxylic Acid Series.

Journal: ACS medicinal chemistry letters

Published: November 26, 2025

Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity.

Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity.

Journal: Cell death discovery

Published: October 14, 2024

Lactate-Induced HBEGF Shedding and EGFR Activation: Paving the Way to a New Anticancer Therapeutic Opportunity.

Lactate-Induced HBEGF Shedding and EGFR Activation: Paving the Way to a New Anticancer Therapeutic Opportunity.

Journal: Cells

Published: July 17, 2024

Peptides inhibiting the assembly of monomeric human l-lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells.

Peptides inhibiting the assembly of monomeric human l-lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells.

Journal: Protein science : a publication of the Protein Society

Published: May 11, 2024

An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer.

An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer.

Journal: European journal of medicinal chemistry

Published: October 27, 2023

Lactate Can Modulate the Antineoplastic Effects of Doxorubicin and Relieve the Drug's Oxidative Damage on Cardiomyocytes.

Lactate Can Modulate the Antineoplastic Effects of Doxorubicin and Relieve the Drug's Oxidative Damage on Cardiomyocytes.

Journal: Cancers

Published: May 24, 2023

Preomic profile of BxPC-3 cells after treatment with BRC4.

Preomic profile of BxPC-3 cells after treatment with BRC4.

Journal: Journal of proteomics

Published: April 11, 2023

Balance Rehabilitation through Robot-Assisted Gait Training in Post-Stroke Patients: A Systematic Review and Meta-Analysis.

Balance Rehabilitation through Robot-Assisted Gait Training in Post-Stroke Patients: A Systematic Review and Meta-Analysis.

Journal: Brain sciences

Published: December 01, 2022

The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination.

The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination.

Journal: International journal of molecular sciences

Published: June 17, 2022

Lactate is a potential promoter of tamoxifen resistance in MCF7 cells.

Lactate is a potential promoter of tamoxifen resistance in MCF7 cells.

Journal: Biochimica et biophysica acta. General subjects

Published: February 08, 2022

Human lactate dehydrogenase A undergoes allosteric transitions under pH conditions inducing the dissociation of the tetrameric enzyme.

Human lactate dehydrogenase A undergoes allosteric transitions under pH conditions inducing the dissociation of the tetrameric enzyme.

Journal: Bioscience reports

Published: November 21, 2021

Showing 1-12 of 32

Last Updated: 09/26/2026