Godwin A. Dziwornu

University Of Cape Town
Rondebosch, WC 7701, South Africa

Last Updated: 09/26/2026

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Found 34 publications

Examination of Coligands in Mefloquine-Metal Complexes Reveals the Structural Determinants of Activity against Plasmodium falciparum and Schistosoma mansoni.

Examination of Coligands in Mefloquine-Metal Complexes Reveals the Structural Determinants of Activity against Plasmodium falciparum and Schistosoma mansoni.

Journal: Journal of medicinal chemistry

Published: March 11, 2026

Optimization of 2,8-Diaryl-1,5-naphthyridines as Plasmodium falciparum Phosphatidylinositol 4-Kinase Inhibitors with Improved ADME Profiles and In Vivo Efficacy.

Optimization of 2,8-Diaryl-1,5-naphthyridines as Plasmodium falciparum Phosphatidylinositol 4-Kinase Inhibitors with Improved ADME Profiles and In Vivo Efficacy.

Journal: Journal of medicinal chemistry

Published: October 07, 2025

Repositioning a Human Kinase Platelet-Derived Growth Factor Receptor Alpha Type II Inhibitor for Malaria and Inhibition of Hemozoin Formation.

Repositioning a Human Kinase Platelet-Derived Growth Factor Receptor Alpha Type II Inhibitor for Malaria and Inhibition of Hemozoin Formation.

Journal: ACS medicinal chemistry letters

Published: September 20, 2025

Novel Inhibitors of Plasmodium Phosphatidylinositol 4-kinase IIIβ with Low Propensity for Resistance: Life Cycle Stage Activity and In Vivo Efficacy in a Humanized Mouse Malaria Infection Model.

Novel Inhibitors of Plasmodium Phosphatidylinositol 4-kinase IIIβ with Low Propensity for Resistance: Life Cycle Stage Activity and In Vivo Efficacy in a Humanized Mouse Malaria Infection Model.

Journal: Journal of medicinal chemistry

Published: August 14, 2025

Value Addition to African Natural Product-Based Drug Discovery Initiatives.

Value Addition to African Natural Product-Based Drug Discovery Initiatives.

Journal: Journal of natural products

Published: July 30, 2025

Antiplasmodial activity, phytochemical analysis and in silico study of the leaf extract of Chenopodium opulifolium Koch & Ziz used in Uganda.

Antiplasmodial activity, phytochemical analysis and in silico study of the leaf extract of Chenopodium opulifolium Koch & Ziz used in Uganda.

Journal: BMC complementary medicine and therapies

Published: January 03, 2025

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4-Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria.

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4-Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria.

Journal: Angewandte Chemie (International ed. in English)

Published: December 23, 2024

Benzimidazole analogues active against adult Schistosoma mansoni: SAR analyses, In vivo efficacy in mice, and preliminary mechanistic studies as potential inhibitors of hemozoin formation.

Benzimidazole analogues active against adult Schistosoma mansoni: SAR analyses, In vivo efficacy in mice, and preliminary mechanistic studies as potential inhibitors of hemozoin formation.

Journal: European journal of medicinal chemistry

Published: October 31, 2024

Another decade of antimalarial drug discovery: New targets, tools and molecules.

Another decade of antimalarial drug discovery: New targets, tools and molecules.

Journal: Progress in medicinal chemistry

Published: October 06, 2024

The dichapetalins and dichapetalin-type compounds: structural diversity, bioactivity, and future research perspectives.

The dichapetalins and dichapetalin-type compounds: structural diversity, bioactivity, and future research perspectives.

Journal: Natural product reports

Published: July 04, 2024

2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of Plasmodium falciparum Phosphatidylinositol-4-kinase and Hemozoin Formation with In Vivo Efficacy.

2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of Plasmodium falciparum Phosphatidylinositol-4-kinase and Hemozoin Formation with In Vivo Efficacy.

Journal: Journal of medicinal chemistry

Published: June 25, 2024

Characterization of antimalarial activity of artemisinin-based hybrid drugs.

Characterization of antimalarial activity of artemisinin-based hybrid drugs.

Journal: Antimicrobial agents and chemotherapy

Published: June 20, 2024

Showing 1-12 of 34

Last Updated: 09/26/2026