Gordon Mcmurray

Pfizer Global R&D
Sandwich, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 17 publications

In vitro affinity optimization of an anti-BDNF monoclonal antibody translates to improved potency in targeting chronic pain states in vivo.

In vitro affinity optimization of an anti-BDNF monoclonal antibody translates to improved potency in targeting chronic pain states in vivo.

Journal: mAbs

Published: April 25, 2020

Single-cell RNAseq reveals seven classes of colonic sensory neuron.

Single-cell RNAseq reveals seven classes of colonic sensory neuron.

Journal: Gut

Published: November 12, 2017

Targeting fatty acid amide hydrolase as a therapeutic strategy for antitussive therapy.

Targeting fatty acid amide hydrolase as a therapeutic strategy for antitussive therapy.

Journal: The European respiratory journal

Published: April 13, 2017

Residues W320 and Y328 within the binding site of the μ-opioid receptor influence opiate ligand bias.

Residues W320 and Y328 within the binding site of the μ-opioid receptor influence opiate ligand bias.

Journal: Neuropharmacology

Published: November 07, 2016

Genome-wide association analysis of pain severity in dysmenorrhea identifies association at chromosome 1p13.2, near the nerve growth factor locus.

Genome-wide association analysis of pain severity in dysmenorrhea identifies association at chromosome 1p13.2, near the nerve growth factor locus.

Journal: Pain

Published: July 26, 2016

Selective 5-HT2C receptor agonists: Design and synthesis of pyridazine-fused azepines.

Selective 5-HT2C receptor agonists: Design and synthesis of pyridazine-fused azepines.

Journal: Bioorganic & medicinal chemistry letters

Published: June 01, 2016

Visceral and somatic pain modalities reveal NaV 1.7-independent visceral nociceptive pathways.

Visceral and somatic pain modalities reveal NaV 1.7-independent visceral nociceptive pathways.

Journal: The Journal of physiology

Published: May 23, 2016

Application of an Integrated GPCR SAR-Modeling Platform To Explain the Activation Selectivity of Human 5-HT2C over 5-HT2B.

Application of an Integrated GPCR SAR-Modeling Platform To Explain the Activation Selectivity of Human 5-HT2C over 5-HT2B.

Journal: ACS chemical biology

Published: February 23, 2016

Design, Synthesis, and Evaluation of Tetrasubstituted Pyridines as Potent 5-HT2C Receptor Agonists.

Design, Synthesis, and Evaluation of Tetrasubstituted Pyridines as Potent 5-HT2C Receptor Agonists.

Journal: ACS medicinal chemistry letters

Published: December 07, 2014

Multiparameter optimization in CNS drug discovery: design of pyrimido[4,5-d]azepines as potent 5-hydroxytryptamine 2C (5-HT₂C) receptor agonists with exquisite functional selectivity over 5-HT₂A and 5-HT₂B receptors.

Multiparameter optimization in CNS drug discovery: design of pyrimido[4,5-d]azepines as potent 5-hydroxytryptamine 2C (5-HT₂C) receptor agonists with exquisite functional selectivity over 5-HT₂A and 5-HT₂B receptors.

Journal: Journal of medicinal chemistry

Published: June 01, 2014

The role of TRPM8 in the Guinea-pig bladder-cooling reflex investigated using a novel TRPM8 antagonist.

The role of TRPM8 in the Guinea-pig bladder-cooling reflex investigated using a novel TRPM8 antagonist.

Journal: European journal of pharmacology

Published: November 28, 2013

Co-expression of GRK2 reveals a novel conformational state of the µ-opioid receptor.

Co-expression of GRK2 reveals a novel conformational state of the µ-opioid receptor.

Journal: PloS one

Published: September 26, 2013

Showing 1-12 of 17

Last Updated: 09/26/2026