Gowramma Byran

Ooty, TN, India

Last Updated: 09/26/2026

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Found 29 publications

Computational design, synthesis, and in vitro evaluation of thiadiazole-derived PARP-1 inhibitors.

Computational design, synthesis, and in vitro evaluation of thiadiazole-derived PARP-1 inhibitors.

Journal: Journal of receptor and signal transduction research

Published: July 07, 2026

Structure-based identification of triazole-based PARP1 inhibitors: insights from docking and molecular dynamics simulations.

Structure-based identification of triazole-based PARP1 inhibitors: insights from docking and molecular dynamics simulations.

Journal: Journal of receptor and signal transduction research

Published: December 12, 2025

PARP1 as a Central Node in DNA Repair and Epigenetic Regulation: Implications for Biomarker Discovery and Targeted Therapy in NSCLC.

PARP1 as a Central Node in DNA Repair and Epigenetic Regulation: Implications for Biomarker Discovery and Targeted Therapy in NSCLC.

Journal: Mini reviews in medicinal chemistry

Published: November 24, 2025

PROTAC-Mediated Targeting of PARP via CRBN: Mechanistic Insights, Resistance Challenges, and Therapeutic Advancements.

PROTAC-Mediated Targeting of PARP via CRBN: Mechanistic Insights, Resistance Challenges, and Therapeutic Advancements.

Journal: Mini reviews in medicinal chemistry

Published: October 03, 2025

Heterocyclic Scaffolds in PARP-1 Inhibition: An Emerging Strategy for Targeted Anticancer Therapy.

Heterocyclic Scaffolds in PARP-1 Inhibition: An Emerging Strategy for Targeted Anticancer Therapy.

Journal: Mini reviews in medicinal chemistry

Published: September 10, 2025

Design and Evaluation of Naphthoxy and Phenoxy amide as Potential PARP 1 inhibitors: Molecular Docking and In Vitro Analysis.

Design and Evaluation of Naphthoxy and Phenoxy amide as Potential PARP 1 inhibitors: Molecular Docking and In Vitro Analysis.

Journal: Current medicinal chemistry

Published: July 29, 2025

Targeting TNBC metastasis: In-silico identification of natural origin ROCK inhibitors via virtual screening, ADMET profiling, MM-GBSA, DFT, and molecular dynamics.

Targeting TNBC metastasis: In-silico identification of natural origin ROCK inhibitors via virtual screening, ADMET profiling, MM-GBSA, DFT, and molecular dynamics.

Journal: Computational biology and chemistry

Published: May 07, 2025

Breaking Barriers in Breast Cancer: Multi-Targeted Therapeutic Insights.

Breaking Barriers in Breast Cancer: Multi-Targeted Therapeutic Insights.

Journal: Mini reviews in medicinal chemistry

Published: April 22, 2025

A Pharmacological Update of Oxadiazole Derivatives: A Review.

A Pharmacological Update of Oxadiazole Derivatives: A Review.

Journal: Current topics in medicinal chemistry

Published: August 31, 2024

Understanding DNA and PARP in Cancer: Tackling Inhibitor Resistance.

Understanding DNA and PARP in Cancer: Tackling Inhibitor Resistance.

Journal: Drug metabolism and bioanalysis letters

Published: July 30, 2024

Understanding Tankyrase Inhibitors and Their Role in the Management of Different Cancer.

Understanding Tankyrase Inhibitors and Their Role in the Management of Different Cancer.

Journal: Current cancer drug targets

Published: June 11, 2024

Targeting STAT3 Enzyme for Cancer Treatment.

Targeting STAT3 Enzyme for Cancer Treatment.

Journal: Mini reviews in medicinal chemistry

Published: March 20, 2023

Showing 1-12 of 29

Last Updated: 09/26/2026