Graciela S. Mahler

Montevideo, MO, Uruguay

Last Updated: 09/26/2026

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Found 24 publications

New derivatives of 6-nitrocoumarin-3-thiosemicarbazone exhibit improved antiparasitic activity in the placenta against Trypanosoma cruzi and Toxoplasma gondii.

New derivatives of 6-nitrocoumarin-3-thiosemicarbazone exhibit improved antiparasitic activity in the placenta against Trypanosoma cruzi and Toxoplasma gondii.

Journal: Antimicrobial agents and chemotherapy
Published: August 07, 2025

Cefiderocol "under siege"? Understanding the rise of NDM-mediated resistance to novel agents.

Cefiderocol "under siege"? Understanding the rise of NDM-mediated resistance to novel agents.

Journal: Chemical science
Published: March 19, 2025

Impact of tebipenem pivoxil on the intestinal microbiota and on establishment of colonization with carbapenem-resistant Klebsiella pneumoniae in mice.

Impact of tebipenem pivoxil on the intestinal microbiota and on establishment of colonization with carbapenem-resistant Klebsiella pneumoniae in mice.

Journal: Microbiology spectrum
Published: March 14, 2025

Novel enantiopure δ-thiolactones: synthesis, structural characterization, and reactivity studies.

Novel enantiopure δ-thiolactones: synthesis, structural characterization, and reactivity studies.

Journal: RSC advances
Published: October 31, 2024

Rational Design of Benzobisheterocycle Metallo-β-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes.

Rational Design of Benzobisheterocycle Metallo-β-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes.

Journal: Journal of medicinal chemistry
Published: February 19, 2024

Correction: 2-Mercaptomethyl-thiazolidines use conserved aromatic-S interactions to achieve broad-range inhibition of metallo-β-lactamases.

Correction: 2-Mercaptomethyl-thiazolidines use conserved aromatic-S interactions to achieve broad-range inhibition of metallo-β-lactamases.

Journal: Chemical science
Published: August 03, 2023

A novel palladium complex with a coumarin-thiosemicarbazone hybrid ligand inhibits Trypanosoma cruzi release from host cells and lowers the parasitemia in vivo.

A novel palladium complex with a coumarin-thiosemicarbazone hybrid ligand inhibits Trypanosoma cruzi release from host cells and lowers the parasitemia in vivo.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry
Published: March 01, 2023

Thioester deprotection using a biomimetic NCL approach.

Thioester deprotection using a biomimetic NCL approach.

Journal: Frontiers in chemistry
Published: May 02, 2022

Structure-Based Bioisosterism Design, Synthesis, Biological Evaluation and In Silico Studies of Benzamide Analogs as Potential Anthelmintics.

Structure-Based Bioisosterism Design, Synthesis, Biological Evaluation and In Silico Studies of Benzamide Analogs as Potential Anthelmintics.

Journal: Molecules (Basel, Switzerland)
Published: March 15, 2022

A new procedure for thioester deprotection using thioglycolic acid in both homogeneous and heterogeneous phase.

A new procedure for thioester deprotection using thioglycolic acid in both homogeneous and heterogeneous phase.

Journal: Tetrahedron
Published: November 08, 2021

Selenosemicarbazone Metal Complexes as Potential Metal-based Drugs.

Selenosemicarbazone Metal Complexes as Potential Metal-based Drugs.

Journal: Current medicinal chemistry
Published: October 04, 2021

Increased sensitivity of an infrared motility assay for nematicide discovery.

Increased sensitivity of an infrared motility assay for nematicide discovery.

Journal: microPublication biology
Published: September 10, 2021
Showing 1-12 of 24

Last Updated: 09/26/2026