Graeme L. Fraser

Hamilton, ON, Canada

Last Updated: 09/26/2026

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Found 50 publications

Optimization of METTL3 Inhibitors for the Treatment of Solid Tumors and AML.

Optimization of METTL3 Inhibitors for the Treatment of Solid Tumors and AML.

Journal: Journal of medicinal chemistry

Published: April 14, 2026

FFAR2 activation induces IL-22-dependent intestinal immune responses to suppress CNS autoimmunity.

FFAR2 activation induces IL-22-dependent intestinal immune responses to suppress CNS autoimmunity.

Journal: EMBO molecular medicine

Published: January 20, 2026

Clinical Pharmacokinetics, Mass Balance and Metabolism of Fezolinetant in Postmenopausal Women.

Clinical Pharmacokinetics, Mass Balance and Metabolism of Fezolinetant in Postmenopausal Women.

Journal: European journal of drug metabolism and pharmacokinetics

Published: October 31, 2025

Primary refractory disease in large B-cell lymphoma: definition and outcomes from a secondary analysis of the LY.12 clinical trial.

Primary refractory disease in large B-cell lymphoma: definition and outcomes from a secondary analysis of the LY.12 clinical trial.

Journal: Blood advances

Published: September 24, 2025

Immunogenicity and safety of a third and subsequent COVID-19 vaccine doses in patients with plasma cell dyscrasias.

Immunogenicity and safety of a third and subsequent COVID-19 vaccine doses in patients with plasma cell dyscrasias.

Journal: Blood advances

Published: August 18, 2025

Activation of Intestinal Type 3 Innate Lymphoid Cells and Regulatory T Cells Through Free Fatty Acid Receptor 2 Ameliorates Type 1 Diabetes in Mice.

Activation of Intestinal Type 3 Innate Lymphoid Cells and Regulatory T Cells Through Free Fatty Acid Receptor 2 Ameliorates Type 1 Diabetes in Mice.

Journal: Diabetes

Published: August 07, 2025

Immunogenicity and Safety of Third, Fourth, and Subsequent COVID-19 Vaccine Doses in Recipients of Hematopoietic Cell Transplantation and Cellular Therapy.

Immunogenicity and Safety of Third, Fourth, and Subsequent COVID-19 Vaccine Doses in Recipients of Hematopoietic Cell Transplantation and Cellular Therapy.

Journal: Transplantation and cellular therapy

Published: July 10, 2025

Concentration-QTc Modeling to Support Clinical Development of Fezolinetant.

Concentration-QTc Modeling to Support Clinical Development of Fezolinetant.

Journal: Clinical pharmacology in drug development

Published: June 23, 2025

Secondary Malignancies Following CAR T-Cell Therapy for B-Cell Malignancies: A Retrospective Analysis.

Secondary Malignancies Following CAR T-Cell Therapy for B-Cell Malignancies: A Retrospective Analysis.

Journal: EJHaem

Published: May 09, 2025

Incremental immunogenicity of multiple doses of SARS-CoV-2 vaccination in patients with haematological malignancies.

Incremental immunogenicity of multiple doses of SARS-CoV-2 vaccination in patients with haematological malignancies.

Journal: British journal of haematology

Published: March 18, 2025

Longitudinal changes in cognition in older individuals receiving lymphoma-directed therapy: A pilot feasibility study.

Longitudinal changes in cognition in older individuals receiving lymphoma-directed therapy: A pilot feasibility study.

Journal: Journal of geriatric oncology

Published: February 04, 2025

Discovery, Optimization, and Preclinical Pharmacology of EP652, a METTL3 Inhibitor with Efficacy in Liquid and Solid Tumor Models.

Discovery, Optimization, and Preclinical Pharmacology of EP652, a METTL3 Inhibitor with Efficacy in Liquid and Solid Tumor Models.

Journal: Journal of medicinal chemistry

Published: January 30, 2025

Showing 1-12 of 50

Last Updated: 09/26/2026