Graeme S. Milligan
Glasgow, SCT G128QQ, United Kingdom
Last Updated: 09/26/2026
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Found 157 publications
Allosteric ligands with distinct properties uncover tissue-specific physiological regulation mediated by free fatty acid receptor 2.
Journal: Science signaling
Published: June 30, 2026
Illuminating proinflammatory myeloid cells with PET tracers targeting GPR84.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: May 21, 2026
Mechanism of GPR84 allosteric modulation at a helix 8-proximate site.
Journal: bioRxiv : the preprint server for biology
Published: April 17, 2026
Discovery, Structure-Activity Relationship, and Functional Characterization of a Chromenopyrrole Series as Orthosteric Antagonists of GPR84.
Journal: Journal of medicinal chemistry
Published: March 23, 2026
Shaping Antimalarials: A Geometry-First Approach to PfCLK3 Covalent Inhibitors.
Journal: Journal of medicinal chemistry
Published: January 31, 2026
Steroid Recognition in Adhesion GPCRs: A Structural and Pharmacological Perspective.
Journal: Pharmacology research & perspectives
Published: October 23, 2025
Steric control of signaling bias in the immunometabolic receptor GPR84.
Journal: bioRxiv : the preprint server for biology
Published: August 06, 2025
Lysine targeting covalent inhibitors of malarial kinase PfCLK3.
Journal: RSC medicinal chemistry
Published: April 17, 2025
Targeting PfCLK3 with Covalent Inhibitors: A Novel Strategy for Malaria Treatment.
Journal: Journal of medicinal chemistry
Published: October 23, 2024
Biased constitutive signaling of the G protein-coupled receptor GPR35 suppresses gut barrier permeability.
Journal: The Journal of biological chemistry
Published: September 18, 2024
Allosteric modulation and biased signalling at free fatty acid receptor 2.
Journal: Nature
Published: August 08, 2024
Last Updated: 09/26/2026