Graham Duddy

GlaxoSmithKline Pharmaceuticals R&D
Harlow, ENG, United Kingdom

Last Updated: 09/26/2026

Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 11 publications

Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines.

Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines.

Journal: Scientific reports
Published: April 03, 2024

Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis.

Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis.

Journal: Nature
Published: March 19, 2024

Pathological mechanisms and candidate therapeutic approaches in the hearing loss of mice carrying human MIR96 mutations.

Pathological mechanisms and candidate therapeutic approaches in the hearing loss of mice carrying human MIR96 mutations.

Journal: Genome medicine
Published: March 07, 2024

Epi-microRNA mediated metabolic reprogramming counteracts hypoxia to preserve affinity maturation.

Epi-microRNA mediated metabolic reprogramming counteracts hypoxia to preserve affinity maturation.

Journal: Nature communications
Published: December 04, 2023

Donor template delivery by recombinant adeno-associated virus for the production of knock-in mice.

Donor template delivery by recombinant adeno-associated virus for the production of knock-in mice.

Journal: BMC biology
Published: September 15, 2023

Epi-microRNA mediated metabolic reprogramming ensures affinity maturation.

Epi-microRNA mediated metabolic reprogramming ensures affinity maturation.

Journal: bioRxiv : the preprint server for biology
Published: August 23, 2023

Tumors induce de novo steroid biosynthesis in T cells to evade immunity.

Tumors induce de novo steroid biosynthesis in T cells to evade immunity.

Journal: Nature communications
Published: April 05, 2020

Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation.

Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation.

Journal: Cell
Published: January 10, 2018

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.

Journal: eLife
Published: November 03, 2015

Characterisation of a K390R ITK kinase dead transgenic mouse--implications for ITK as a therapeutic target.

Characterisation of a K390R ITK kinase dead transgenic mouse--implications for ITK as a therapeutic target.

Journal: PloS one
Published: June 09, 2014

Targeting apoptosis signalling kinase-1 (ASK-1) does not prevent the development of neuropathy in streptozotocin-induced diabetic mice.

Targeting apoptosis signalling kinase-1 (ASK-1) does not prevent the development of neuropathy in streptozotocin-induced diabetic mice.

Journal: PloS one
Published: January 29, 2014
Showing 1-11 of 11

Last Updated: 09/26/2026