Graham M. Wheeler

90 Tottenham Court Road, W1T 4TJ
London, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 27 publications

A first-in-human phase I clinical trial investigating the safety and efficacy of repeat dosing MSCTRAIL cell therapy in addition to chemotherapy and immunotherapy in patients with advanced lung cancer.

A first-in-human phase I clinical trial investigating the safety and efficacy of repeat dosing MSCTRAIL cell therapy in addition to chemotherapy and immunotherapy in patients with advanced lung cancer.

Journal: Cytotherapy

Published: June 16, 2025

A Dose-Finding Design for Drug Combinations Using a Bayesian 4 Parameter Logistic Model With Penalised D-Optimality.

A Dose-Finding Design for Drug Combinations Using a Bayesian 4 Parameter Logistic Model With Penalised D-Optimality.

Journal: Pharmaceutical statistics

Published: January 17, 2025

Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) trial: study protocol for a multicentre, double-blinded, placebo-controlled, phase IIa trial.

Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) trial: study protocol for a multicentre, double-blinded, placebo-controlled, phase IIa trial.

Journal: BMJ open

Published: January 08, 2025

Protocol for the EACH trial: a multicentre phase II study evaluating the safety and antitumour activity of the combination of avelumab, an anti-PD-L1 agent, and cetuximab, as any line treatment for patients with recurrent/metastatic head and neck squamous cell cancer (HNSCC) in the UK.

Protocol for the EACH trial: a multicentre phase II study evaluating the safety and antitumour activity of the combination of avelumab, an anti-PD-L1 agent, and cetuximab, as any line treatment for patients with recurrent/metastatic head and neck squamous cell cancer (HNSCC) in the UK.

Journal: BMJ open

Published: November 27, 2023

Correction: Medicines and Healthcare products Regulatory Agency's "Consultation on proposals for legislative changes for clinical trials": a response from the Trials Methodology Research Partnership Adaptive Designs Working Group, with a focus on data sharing.

Correction: Medicines and Healthcare products Regulatory Agency's "Consultation on proposals for legislative changes for clinical trials": a response from the Trials Methodology Research Partnership Adaptive Designs Working Group, with a focus on data sharing.

Journal: Trials

Published: November 22, 2023

Medicines and Healthcare products Regulatory Agency's "Consultation on proposals for legislative changes for clinical trials": a response from the Trials Methodology Research Partnership Adaptive Designs Working Group, with a focus on data sharing.

Medicines and Healthcare products Regulatory Agency's "Consultation on proposals for legislative changes for clinical trials": a response from the Trials Methodology Research Partnership Adaptive Designs Working Group, with a focus on data sharing.

Journal: Trials

Published: October 27, 2022

Visualising harms in publications of randomised controlled trials: consensus and recommendations.

Visualising harms in publications of randomised controlled trials: consensus and recommendations.

Journal: BMJ (Clinical research ed.)

Published: May 16, 2022

"Improving the performance of Bayesian logistic regression model with overdose control in oncology dose-finding studies" by Hongtao Zhang, Alan Chiang, and Jixian Wang.

"Improving the performance of Bayesian logistic regression model with overdose control in oncology dose-finding studies" by Hongtao Zhang, Alan Chiang, and Jixian Wang.

Journal: Statistics in medicine

Published: May 13, 2022

Addition of probenecid to oral β-lactam antibiotics: a systematic review and meta-analysis.

Addition of probenecid to oral β-lactam antibiotics: a systematic review and meta-analysis.

Journal: The Journal of antimicrobial chemotherapy

Published: March 18, 2022

Effectiveness and cost-effectiveness of referral to a commercial open group behavioural weight management programme in adults with overweight and obesity: 5-year follow-up of the WRAP randomised controlled trial.

Effectiveness and cost-effectiveness of referral to a commercial open group behavioural weight management programme in adults with overweight and obesity: 5-year follow-up of the WRAP randomised controlled trial.

Journal: The Lancet. Public health

Published: February 24, 2022

Early phase clinical trials extension to guidelines for the content of statistical analysis plans.

Early phase clinical trials extension to guidelines for the content of statistical analysis plans.

Journal: BMJ (Clinical research ed.)

Published: February 08, 2022

Durable Responses and Low Toxicity After Fast Off-Rate CD19 Chimeric Antigen Receptor-T Therapy in Adults With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia.

Durable Responses and Low Toxicity After Fast Off-Rate CD19 Chimeric Antigen Receptor-T Therapy in Adults With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Published: August 31, 2021

Showing 1-12 of 27

Last Updated: 09/26/2026