Grazia D. Raffa

Rome, 00185, Italy

Last Updated: 09/26/2026

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Found 21 publications

Exosome-mediated decay of unstable long extended precursors of human telomerase RNA is dependent on 5'-cap trimethylation.

Exosome-mediated decay of unstable long extended precursors of human telomerase RNA is dependent on 5'-cap trimethylation.

Journal: Genes & development

Published: June 16, 2025

Mutational analysis of the Drosophila CMG helicase reveals relationships among chromosome integrity and the maintenance of spindle and centrosome structure.

Mutational analysis of the Drosophila CMG helicase reveals relationships among chromosome integrity and the maintenance of spindle and centrosome structure.

Journal: Genetics

Published: April 15, 2025

Maintaining Telomeres without Telomerase in Drosophila: Novel Mechanisms and Rapid Evolution to Save a Genus.

Maintaining Telomeres without Telomerase in Drosophila: Novel Mechanisms and Rapid Evolution to Save a Genus.

Journal: Cold Spring Harbor perspectives in biology

Published: December 18, 2024

Correction to: 'The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence' (2016), by Burla et al.

Correction to: 'The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence' (2016), by Burla et al.

Journal: Open biology

Published: November 12, 2024

TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration.

TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration.

Journal: Nucleic acids research

Published: June 29, 2022

The S-adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening.

The S-adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening.

Journal: FEBS letters

Published: October 16, 2021

Atomic Force Microscopy Reveals that the Drosophila Telomere-Capping Protein Verrocchio Is a Single-Stranded DNA-Binding Protein.

Atomic Force Microscopy Reveals that the Drosophila Telomere-Capping Protein Verrocchio Is a Single-Stranded DNA-Binding Protein.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: April 13, 2021

TGS1 mediates 2,2,7-trimethyl guanosine capping of the human telomerase RNA to direct telomerase dependent telomere maintenance.

TGS1 mediates 2,2,7-trimethyl guanosine capping of the human telomerase RNA to direct telomerase dependent telomere maintenance.

Journal: Nature communications

Published: November 09, 2020

Silence at the End: How Drosophila Regulates Expression and Transposition of Telomeric Retroelements.

Silence at the End: How Drosophila Regulates Expression and Transposition of Telomeric Retroelements.

Journal: Journal of molecular biology

Published: February 19, 2020

Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye development.

Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye development.

Journal: PLoS genetics

Published: February 13, 2020

Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation.

Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation.

Journal: Cell reports

Published: June 28, 2019

Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease.

Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease.

Journal: Molecular cell

Published: September 14, 2018

Showing 1-12 of 21

Last Updated: 09/26/2026