Gregoire Vuagniaux
Lausanne, VD 1006, Switzerland
Last Updated: 09/26/2026
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Found 18 publications
Evaluation of the microbiota-sparing properties of the anti-staphylococcal antibiotic afabicin.
Journal: The Journal of antimicrobial chemotherapy
Published: January 14, 2023
Exploratory window-of-opportunity trial to investigate the tumor pharmacokinetics/pharmacodynamics of the IAP antagonist Debio 1143 in patients with head and neck cancer.
Journal: Clinical and translational science
Published: October 05, 2020
Phase I Trial of Debio 1143, an Antagonist of Inhibitor of Apoptosis Proteins, Combined with Cisplatin Chemoradiotherapy in Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: February 03, 2020
The inhibitor of apoptosis proteins antagonist Debio 1143 promotes the PD-1 blockade-mediated HIV load reduction in blood and tissues of humanized mice.
Journal: PloS one
Published: September 04, 2019
DEBIO 1143, an IAP inhibitor, reverses carboplatin resistance in ovarian cancer cells and triggers apoptotic or necroptotic cell death.
Journal: Scientific reports
Published: August 01, 2018
Nuclear Imaging Study of the Pharmacodynamic Effects of Debio 1143, an Antagonist of Multiple Inhibitor of Apoptosis Proteins (IAPs), in a Triple-Negative Breast Cancer Model.
Journal: Contrast media & molecular imaging
Published: July 13, 2018
SMAC Mimetic Debio 1143 and Ablative Radiation Therapy Synergize to Enhance Antitumor Immunity against Lung Cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: January 19, 2018
HCV1b genome evolution under selective pressure of the cyclophilin inhibitor alisporivir during the DEB-025-HCV-203 phase II clinical trial.
Journal: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Published: March 24, 2016
A Pathogen-Selective Antibiotic Minimizes Disturbance to the Microbiome.
Journal: Antimicrobial agents and chemotherapy
Published: March 08, 2016
SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells.
Journal: Oncotarget
Published: September 25, 2015
The radiosensitizing activity of the SMAC-mimetic, Debio 1143, is TNFα-mediated in head and neck squamous cell carcinoma.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Published: April 21, 2015
Last Updated: 09/26/2026