Gu M. He

Chengdu, 610041, China

Last Updated: 09/26/2026

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Found 138 publications

Discovery of a potent PROTAC targeting G9a suppresses proliferation of triple-negative breast cancer cells and psoriasis-like keratinocytes.

Discovery of a potent PROTAC targeting G9a suppresses proliferation of triple-negative breast cancer cells and psoriasis-like keratinocytes.

Journal: European journal of medicinal chemistry

Published: May 08, 2026

Piezo Family: From Structure to Therapeutic Agents in Cancer.

Piezo Family: From Structure to Therapeutic Agents in Cancer.

Journal: Journal of medicinal chemistry

Published: February 22, 2026

Decoding Class III Phosphatidylinositol 3-Kinase (PtdIns3K) Regulation: Mechanistic Insights and Therapeutic Opportunities.

Decoding Class III Phosphatidylinositol 3-Kinase (PtdIns3K) Regulation: Mechanistic Insights and Therapeutic Opportunities.

Journal: ChemMedChem

Published: November 14, 2025

Discovery of indolinone-based covalent ULK1 inhibitors that suppressed autophagy and induced apoptosis against colorectal carcinoma.

Discovery of indolinone-based covalent ULK1 inhibitors that suppressed autophagy and induced apoptosis against colorectal carcinoma.

Journal: European journal of medicinal chemistry

Published: October 22, 2025

Deciphering the rules of regulated cell death subroutines by in silico methods.

Deciphering the rules of regulated cell death subroutines by in silico methods.

Journal: Journal of advanced research

Published: August 18, 2025

Cholesterol modified defense peptide as an EMP2-siRNA delivery system for synergistic immunogene therapy against breast cancer.

Cholesterol modified defense peptide as an EMP2-siRNA delivery system for synergistic immunogene therapy against breast cancer.

Journal: Materials today. Bio

Published: July 21, 2025

Design, synthesis, and biological evaluation of a dual-action agent targeting bromodomain and extraterminal domain and H2S release for the treatment of hepatic and pulmonary injury.

Design, synthesis, and biological evaluation of a dual-action agent targeting bromodomain and extraterminal domain and H2S release for the treatment of hepatic and pulmonary injury.

Journal: European journal of medicinal chemistry

Published: April 12, 2025

T-cell immunoglobulin and mucin domain-containing protein 3-mediated immunomodulation in myeloid cells and keratinocytes in the development of severe acne.

T-cell immunoglobulin and mucin domain-containing protein 3-mediated immunomodulation in myeloid cells and keratinocytes in the development of severe acne.

Journal: Molecular biomedicine

Published: February 13, 2025

FAK mediates mechanical signaling to maintain epithelial homeostasis through YAP/TAZ-TEADs.

FAK mediates mechanical signaling to maintain epithelial homeostasis through YAP/TAZ-TEADs.

Journal: Histochemistry and cell biology

Published: January 21, 2025

Research Advances in Chaperone-Mediated Autophagy (CMA) and CMA-Based Protein Degraders.

Research Advances in Chaperone-Mediated Autophagy (CMA) and CMA-Based Protein Degraders.

Journal: Journal of medicinal chemistry

Published: January 17, 2025

Z-DNA-binding protein 1-mediated programmed cell death: Mechanisms and therapeutic implications.

Z-DNA-binding protein 1-mediated programmed cell death: Mechanisms and therapeutic implications.

Journal: Chinese medical journal

Published: January 08, 2025

Use of Janus kinase inhibitors in patients aged ≤18 years with alopecia areata: A systematic review and meta-analysis.

Use of Janus kinase inhibitors in patients aged ≤18 years with alopecia areata: A systematic review and meta-analysis.

Journal: Journal of the American Academy of Dermatology

Published: December 08, 2024

Showing 1-12 of 138

Last Updated: 09/26/2026