Guanghao M. Zhu

1200 Cailun Road
Shanghai, 201203, China

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 36 publications

Targeted degradation of hepatic KEAP1 mitigates drug-induced liver injury via dual boosting NRF2 and PGAM5 signaling.

Targeted degradation of hepatic KEAP1 mitigates drug-induced liver injury via dual boosting NRF2 and PGAM5 signaling.

Journal: Redox biology

Published: June 12, 2026

A Rationally Engineered MAGL-Activatable Fluorogenic Probe Enables Efficient Discovery of Anti-Inflammatory and Hepatoprotective Agents.

A Rationally Engineered MAGL-Activatable Fluorogenic Probe Enables Efficient Discovery of Anti-Inflammatory and Hepatoprotective Agents.

Journal: Journal of medicinal chemistry

Published: May 30, 2026

Salvianolic acid B attenuates drug-induced liver injury in an Nrf2-dependent mechanism via covalently modifying Keap1 at Cys395/Cys434.

Salvianolic acid B attenuates drug-induced liver injury in an Nrf2-dependent mechanism via covalently modifying Keap1 at Cys395/Cys434.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: February 15, 2026

In situ mapping of HSA reabsorption by a NIR fluorogenic sensor as a practical phenotypic assay for nephroprotective drug discovery.

In situ mapping of HSA reabsorption by a NIR fluorogenic sensor as a practical phenotypic assay for nephroprotective drug discovery.

Journal: Biosensors & bioelectronics

Published: December 31, 2025

Isoliquiritigenin attenuates cisplatin-induced hearing loss and ototoxicity by activating the Keap1-Nrf2-ARE pathway.

Isoliquiritigenin attenuates cisplatin-induced hearing loss and ototoxicity by activating the Keap1-Nrf2-ARE pathway.

Journal: Free radical biology & medicine

Published: August 15, 2025

The Identification and Synthesis of New Sea Cucumber Peptides Leveraging Peptidomics Technology, along with their Anti-Parkinson's Disease Efficacy.

The Identification and Synthesis of New Sea Cucumber Peptides Leveraging Peptidomics Technology, along with their Anti-Parkinson's Disease Efficacy.

Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

Published: April 29, 2025

Madecassoside exerts anti-neurodegeneration effects in protein l-isoaspartyl methyltransferase deficient mice via targeting PRDX2-mediated oxidative stress and inflammation.

Madecassoside exerts anti-neurodegeneration effects in protein l-isoaspartyl methyltransferase deficient mice via targeting PRDX2-mediated oxidative stress and inflammation.

Journal: Biochemical pharmacology

Published: April 26, 2025

Thiazole-fused thiazoliniums with ketone warheads as covalent inhibitors targeting Cys44 of SARS-CoV-2 3CLpro.

Thiazole-fused thiazoliniums with ketone warheads as covalent inhibitors targeting Cys44 of SARS-CoV-2 3CLpro.

Journal: Chemico-biological interactions

Published: April 25, 2025

Discovery of a novel chalcone-derived covalent Keap1 binder for mitigating cisplatin-induced mitochondrial dysfunction and nephrotoxicity.

Discovery of a novel chalcone-derived covalent Keap1 binder for mitigating cisplatin-induced mitochondrial dysfunction and nephrotoxicity.

Journal: Redox biology

Published: April 09, 2025

An optimized CYP3A4-activatable fluorogenic sensor for in situ functional imaging and multi-dimensional inhibitor assessment.

An optimized CYP3A4-activatable fluorogenic sensor for in situ functional imaging and multi-dimensional inhibitor assessment.

Journal: Chemical science

Published: March 06, 2025

Pectolinarigenin mitigates 5-FU-induced intestinal mucositis via suppressing ferroptosis through activating PPARγ/GPX4 signaling.

Pectolinarigenin mitigates 5-FU-induced intestinal mucositis via suppressing ferroptosis through activating PPARγ/GPX4 signaling.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: December 28, 2024

Rational engineering of isoform-specific hSULT1E1 fluorogenic substrates for functional analysis and inhibitor screening.

Rational engineering of isoform-specific hSULT1E1 fluorogenic substrates for functional analysis and inhibitor screening.

Journal: Biosensors & bioelectronics

Published: October 18, 2024

Showing 1-12 of 36

Last Updated: 09/26/2026