Guanghui Wang
Jiangsu Key Laboratory Of Drug Discovery And Translational Research For Brain Diseases
Suzhou, China
Suzhou, China
Last Updated: 09/26/2026
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Found 54 publications
Structural insights into the MLH1-FAN1 interaction reveal an uncharacterized binding interface on MLH1.
Journal: Nature communications
Published: November 21, 2025
Lysine acetyltransferase 8-mediated histone acetylation, regulated by GBA1, is associated with lysosomal function related to α-Synuclein pathology.
Journal: Cell death & disease
Published: June 10, 2025
PLK2 disrupts autophagic flux to promote SNCA/α-synuclein pathology.
Journal: Autophagy
Published: January 08, 2025
Loss of NgBR causes neuronal damage through decreasing KAT7-mediated RFX1 acetylation and FGF1 expression.
Journal: Cellular and molecular life sciences : CMLS
Published: November 08, 2024
Targeting chaperone-mediated autophagy in neurodegenerative diseases: mechanisms and therapeutic potential.
Journal: Acta pharmacologica Sinica
Published: July 03, 2024
Polo-like kinase 2 promotes microglial activation via regulation of the HSP90α/IKKβ pathway.
Journal: Cell reports
Published: April 03, 2024
The NTE domain of PTENα/β promotes cancer progression by interacting with WDR5 via its SSSRRSS motif.
Journal: Cell death & disease
Published: February 20, 2024
P7C3 suppresses astrocytic senescence to protect dopaminergic neurons: Implication in the mouse model of Parkinson's disease.
Journal: CNS neuroscience & therapeutics
Published: November 02, 2023
Inhibition of EHMT1/2 rescues synaptic damage and motor impairment in a PD mouse model.
Journal: Cellular and molecular life sciences : CMLS
Published: October 17, 2023
Deficient chaperone-mediated autophagy facilitates LPS-induced microglial activation via regulation of the p300/NF-κB/NLRP3 pathway.
Journal: Science advances
Published: October 06, 2023
Last Updated: 09/26/2026