Guangying Du

Key Laboratory Of Molecular Pharmacology And Drug Evaluation
Yantai, 264005, China

Last Updated: 09/26/2026

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Found 22 publications

Targeting ME1 rescues redox-metabolic coordination in ALS: A core effector of NRF2-directed therapy.

Targeting ME1 rescues redox-metabolic coordination in ALS: A core effector of NRF2-directed therapy.

Journal: Neuropharmacology

Published: December 08, 2025

Pharmacodynamics, safety pharmacology and local tolerance of rotigotine behenate extended-release microspheres.

Pharmacodynamics, safety pharmacology and local tolerance of rotigotine behenate extended-release microspheres.

Journal: Toxicology and applied pharmacology

Published: March 24, 2025

Synthesis and evaluation of novel 5-HT2A receptor inverse agonist with excellent in vivo antipsychotic efficacy and superior tissue distribution for treatment of Parkinson's disease psychosis.

Synthesis and evaluation of novel 5-HT2A receptor inverse agonist with excellent in vivo antipsychotic efficacy and superior tissue distribution for treatment of Parkinson's disease psychosis.

Journal: European journal of medicinal chemistry

Published: March 11, 2025

Design, synthesis, and biological evaluation of novel molecules as potent inhibitors of indoleamine 2,3-dioxygenase 1.

Design, synthesis, and biological evaluation of novel molecules as potent inhibitors of indoleamine 2,3-dioxygenase 1.

Journal: Molecular diversity

Published: September 06, 2024

Non-clinical pharmacology and toxicology studies of LPM6690061, a novel 5-hydroxytryptamine (5-HT)2A receptor inverse agonist.

Non-clinical pharmacology and toxicology studies of LPM6690061, a novel 5-hydroxytryptamine (5-HT)2A receptor inverse agonist.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Published: January 31, 2023

Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5.

Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5.

Journal: Cell discovery

Published: September 20, 2022

9-Cyclopropylmethoxy-dihydrotetrabenazine and its stereoisomers as vesicular monoamine transporter-2 inhibitors.

9-Cyclopropylmethoxy-dihydrotetrabenazine and its stereoisomers as vesicular monoamine transporter-2 inhibitors.

Journal: Future medicinal chemistry

Published: May 31, 2022

Improving the treatment of Parkinson's disease: Structure-based development of novel 5-HT2A receptor antagonists/inverse agonists.

Improving the treatment of Parkinson's disease: Structure-based development of novel 5-HT2A receptor antagonists/inverse agonists.

Journal: European journal of medicinal chemistry

Published: December 04, 2021

(+)-9-Trifluoroethoxy-α-Dihydrotetrabenazine as a Highly Potent Vesicular Monoamine Transporter 2 Inhibitor for Tardive Dyskinesia.

(+)-9-Trifluoroethoxy-α-Dihydrotetrabenazine as a Highly Potent Vesicular Monoamine Transporter 2 Inhibitor for Tardive Dyskinesia.

Journal: Frontiers in pharmacology

Published: September 03, 2021

Synthesis and analysis of dihydrotetrabenazine derivatives as novel vesicular monoamine transporter 2 inhibitors.

Synthesis and analysis of dihydrotetrabenazine derivatives as novel vesicular monoamine transporter 2 inhibitors.

Journal: European journal of medicinal chemistry

Published: May 08, 2021

Structure and function analysis of a potent human neutralizing antibody CA521FALA against SARS-CoV-2.

Structure and function analysis of a potent human neutralizing antibody CA521FALA against SARS-CoV-2.

Journal: Communications biology

Published: November 04, 2020

Comparison study of different indoleamine-2,3 dioxygenase inhibitors from the perspective of pharmacodynamic effects.

Comparison study of different indoleamine-2,3 dioxygenase inhibitors from the perspective of pharmacodynamic effects.

Journal: International journal of immunopathology and pharmacology

Published: September 23, 2020

Showing 1-12 of 22

Last Updated: 09/26/2026