Guangyu Fang

Bristol, ENG BS81TD, United Kingdom

Last Updated: 09/26/2026

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Found 12 publications

Pharmacological characterization of a novel negative allosteric modulator of NMDA receptors, UBP792.

Pharmacological characterization of a novel negative allosteric modulator of NMDA receptors, UBP792.

Journal: Neuropharmacology

Published: May 15, 2021

Investigation of the structural requirements for N-methyl-D-aspartate receptor positive and negative allosteric modulators based on 2-naphthoic acid.

Investigation of the structural requirements for N-methyl-D-aspartate receptor positive and negative allosteric modulators based on 2-naphthoic acid.

Journal: European journal of medicinal chemistry

Published: October 17, 2018

The NMDA receptor intracellular C-terminal domains reciprocally interact with allosteric modulators.

The NMDA receptor intracellular C-terminal domains reciprocally interact with allosteric modulators.

Journal: Biochemical pharmacology

Published: October 02, 2018

Positive and Negative Allosteric Modulators of N-Methyl-d-aspartate (NMDA) Receptors: Structure-Activity Relationships and Mechanisms of Action.

Positive and Negative Allosteric Modulators of N-Methyl-d-aspartate (NMDA) Receptors: Structure-Activity Relationships and Mechanisms of Action.

Journal: Journal of medicinal chemistry

Published: February 16, 2018

Mechanism and properties of positive allosteric modulation of N-methyl-d-aspartate receptors by 6-alkyl 2-naphthoic acid derivatives.

Mechanism and properties of positive allosteric modulation of N-methyl-d-aspartate receptors by 6-alkyl 2-naphthoic acid derivatives.

Journal: Neuropharmacology

Published: March 29, 2017

A single-channel mechanism for pharmacological potentiation of GluN1/GluN2A NMDA receptors.

A single-channel mechanism for pharmacological potentiation of GluN1/GluN2A NMDA receptors.

Journal: Scientific reports

Published: December 02, 2016

The Startle Disease Mutation E103K Impairs Activation of Human Homomeric α1 Glycine Receptors by Disrupting an Intersubunit Salt Bridge across the Agonist Binding Site.

The Startle Disease Mutation E103K Impairs Activation of Human Homomeric α1 Glycine Receptors by Disrupting an Intersubunit Salt Bridge across the Agonist Binding Site.

Journal: The Journal of biological chemistry

Published: November 14, 2016

Synthesis of a Series of Novel 3,9-Disubstituted Phenanthrenes as Analogues of Known NMDA Receptor Allosteric Modulators.

Synthesis of a Series of Novel 3,9-Disubstituted Phenanthrenes as Analogues of Known NMDA Receptor Allosteric Modulators.

Journal: Synthesis

Published: November 17, 2015

Characterisation of an mGlu8 receptor-selective agonist and antagonist in the lateral and medial perforant path inputs to the dentate gyrus.

Characterisation of an mGlu8 receptor-selective agonist and antagonist in the lateral and medial perforant path inputs to the dentate gyrus.

Journal: Neuropharmacology

Published: September 27, 2012

The NMDA receptor as a target for cognitive enhancement.

The NMDA receptor as a target for cognitive enhancement.

Journal: Neuropharmacology

Published: May 15, 2012

Piperazine-2,3-dicarboxylic acid derivatives as dual antagonists of NMDA and GluK1-containing kainate receptors.

Piperazine-2,3-dicarboxylic acid derivatives as dual antagonists of NMDA and GluK1-containing kainate receptors.

Journal: Journal of medicinal chemistry

Published: November 25, 2011

Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-D-aspartate receptors.

Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-D-aspartate receptors.

Journal: Neurochemistry international

Published: November 18, 2011

Showing 1-12 of 12

Last Updated: 09/26/2026