Guanzhao Wu

758 Hefei Road
Qingdao, 266035, China

Last Updated: 09/26/2026

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Found 26 publications

Correction to "Discovery of Imidazo[2,1-b][1,3,4]thiadiazole-Based MNK Inhibitors with Anti-inflammatory Efficacy via Dual Suppression of eIF4E Phosphorylation and NF-κB Signaling".

Correction to "Discovery of Imidazo[2,1-b][1,3,4]thiadiazole-Based MNK Inhibitors with Anti-inflammatory Efficacy via Dual Suppression of eIF4E Phosphorylation and NF-κB Signaling".

Journal: Journal of medicinal chemistry

Published: May 25, 2026

Discovery of a mitochondria-targeted propranolol conjugate PL37 that induces mitophagy for potent anti-hemangioma activity.

Discovery of a mitochondria-targeted propranolol conjugate PL37 that induces mitophagy for potent anti-hemangioma activity.

Journal: Bioorganic & medicinal chemistry

Published: May 15, 2026

Design, synthesis, and biological evaluation of a multi-layer-linked idebenone derivative targeting mitochondrial dysfunction and neuroinflammation for ischemic stroke.

Design, synthesis, and biological evaluation of a multi-layer-linked idebenone derivative targeting mitochondrial dysfunction and neuroinflammation for ischemic stroke.

Journal: Bioorganic chemistry

Published: May 07, 2026

Discovery of a novel idebenone-rhein hybrid 4c with enhanced NQO1 expression for neuroprotection against cerebral ischemia-reperfusion injury.

Discovery of a novel idebenone-rhein hybrid 4c with enhanced NQO1 expression for neuroprotection against cerebral ischemia-reperfusion injury.

Journal: European journal of medicinal chemistry

Published: April 30, 2026

Discovery of Imidazo[2,1-b][1,3,4]thiadiazole-Based MNK Inhibitors with Anti-inflammatory Efficacy via Dual Suppression of eIF4E Phosphorylation and NF-κB Signaling.

Discovery of Imidazo[2,1-b][1,3,4]thiadiazole-Based MNK Inhibitors with Anti-inflammatory Efficacy via Dual Suppression of eIF4E Phosphorylation and NF-κB Signaling.

Journal: Journal of medicinal chemistry

Published: April 07, 2026

Design, Synthesis, and Structure-Activity Relationship Study of μ-Conotoxin KIIIA toward NaV1.4.

Design, Synthesis, and Structure-Activity Relationship Study of μ-Conotoxin KIIIA toward NaV1.4.

Journal: Journal of medicinal chemistry

Published: March 31, 2026

Impact of Physical Activity on Stroke Risk in Middle-Aged and Older Adults.

Impact of Physical Activity on Stroke Risk in Middle-Aged and Older Adults.

Journal: Brain and behavior

Published: December 21, 2025

The lung-brain axis: elucidating the mechanisms of pulmonary-driven neurological disorders.

The lung-brain axis: elucidating the mechanisms of pulmonary-driven neurological disorders.

Journal: Journal of neuroinflammation

Published: November 09, 2025

Proteome-wide Mendelian Randomization and Colocalization Nominate CD58, PARP1, and Immune Co-stimulatory Pathways as Genetically Supported Targets for Multiple Sclerosis.

Proteome-wide Mendelian Randomization and Colocalization Nominate CD58, PARP1, and Immune Co-stimulatory Pathways as Genetically Supported Targets for Multiple Sclerosis.

Journal: Current neuropharmacology

Published: August 30, 2025

A mitochondria-targeted idebenone derivative W1a mitigates cerebral ischemia-reperfusion injury by preserving mitochondrial integrity and suppressing neuroinflammation.

A mitochondria-targeted idebenone derivative W1a mitigates cerebral ischemia-reperfusion injury by preserving mitochondrial integrity and suppressing neuroinflammation.

Journal: Bioorganic chemistry

Published: July 08, 2025

Idebenone alleviates rotenone-induced mitochondrial dysfunction through mitophagy and mitochondrial biogenesis in muscle cells.

Idebenone alleviates rotenone-induced mitochondrial dysfunction through mitophagy and mitochondrial biogenesis in muscle cells.

Journal: Cellular signalling

Published: June 05, 2025

Discovery of a potential anti-ischemic stroke agent by suppressing ferroptosis through the ATF3/SLC7A11/GPX4 pathway.

Discovery of a potential anti-ischemic stroke agent by suppressing ferroptosis through the ATF3/SLC7A11/GPX4 pathway.

Journal: European journal of medicinal chemistry

Published: April 18, 2025

Showing 1-12 of 26

Last Updated: 09/26/2026