Guido Veit

Montreal, QC H3G1Y6, Canada

Last Updated: 09/26/2026

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Found 27 publications

Triple potentiator combinations increase the functional correction of several CFTR gating mutants.

Triple potentiator combinations increase the functional correction of several CFTR gating mutants.

Journal: npj drug discovery
Published: November 21, 2025

Synthesis and Biological Evaluation of Pyrazole-Pyrimidones as a New Class of Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).

Synthesis and Biological Evaluation of Pyrazole-Pyrimidones as a New Class of Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).

Journal: Journal of medicinal chemistry
Published: August 13, 2024

Editorial: Advancing therapeutic strategies: exploring ABC transporters and chemicals affecting their expression and function for disease treatment.

Editorial: Advancing therapeutic strategies: exploring ABC transporters and chemicals affecting their expression and function for disease treatment.

Journal: Frontiers in pharmacology
Published: April 26, 2024

Readthrough-induced misincorporated amino acid ratios guide mutant-specific therapeutic approaches for two CFTR nonsense mutations.

Readthrough-induced misincorporated amino acid ratios guide mutant-specific therapeutic approaches for two CFTR nonsense mutations.

Journal: Frontiers in pharmacology
Published: February 21, 2024

Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling.

Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling.

Journal: bioRxiv : the preprint server for biology
Published: October 31, 2023

Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling.

Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling.

Journal: Nature communications
Published: November 16, 2022

Editorial: Mechanisms of Novel Drugs and Gene Modifiers in the Treatment of Cystic Fibrosis.

Editorial: Mechanisms of Novel Drugs and Gene Modifiers in the Treatment of Cystic Fibrosis.

Journal: Frontiers in molecular biosciences
Published: June 22, 2022

A Precision Medicine Approach to Optimize Modulator Therapy for Rare CFTR Folding Mutants.

A Precision Medicine Approach to Optimize Modulator Therapy for Rare CFTR Folding Mutants.

Journal: Journal of personalized medicine
Published: June 16, 2021

Discovery of CFTR modulators for the treatment of cystic fibrosis.

Discovery of CFTR modulators for the treatment of cystic fibrosis.

Journal: Expert opinion on drug discovery
Published: April 07, 2021

Elexacaftor co-potentiates the activity of F508del and gating mutants of CFTR.

Elexacaftor co-potentiates the activity of F508del and gating mutants of CFTR.

Journal: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
Published: December 23, 2020

Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination.

Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination.

Journal: JCI insight
Published: May 06, 2020

Mutation-specific dual potentiators maximize rescue of CFTR gating mutants.

Mutation-specific dual potentiators maximize rescue of CFTR gating mutants.

Journal: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
Published: August 27, 2019
Showing 1-12 of 27

Last Updated: 09/26/2026