Guillaume Lessene
Melbourne, VIC, Australia
Last Updated: 09/26/2026
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Found 79 publications
Emerging challenges, mechanisms, and therapeutic opportunities in cell death.
Journal: Cell chemical biology
Published: June 23, 2026
BCL-2 and MCL1 co-inhibition enhances glucocorticoid therapy in preclinical models of infant KMT2A-rearranged acute lymphoblastic leukaemia.
Journal: British journal of haematology
Published: October 26, 2025
The benchmarking and application of tag-degraders in vivo to validate therapeutic targets.
Journal: Nature communications
Published: June 12, 2025
Differential regulation of BAX and BAK apoptotic activity revealed by small molecules.
Journal: Science advances
Published: March 05, 2025
A novel PLpro inhibitor improves outcomes in a pre-clinical model of long COVID.
Journal: Nature communications
Published: December 18, 2024
Re-appraising assays on permeabilized blood cancer cells testing venetoclax or other BH3 mimetic agents selectively targeting pro-survival BCL2 proteins.
Journal: Cell death and differentiation
Published: July 05, 2024
Key residues in the VDAC2-BAK complex can be targeted to modulate apoptosis.
Journal: PLoS biology
Published: December 23, 2023
Correction: ATF3 Repression of BCL-XL Determines Apoptotic Sensitivity to HDAC Inhibitors Across Tumor Types.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: September 15, 2023
Correction to: The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells.
Journal: Cell death and differentiation
Published: February 24, 2023
Last Updated: 09/26/2026