Guo-chun Zhou

Nanjing, 211816, China

Last Updated: 09/26/2026

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Found 30 publications

Anti-zika virus agents and viral RdRp enzymatic inhibitors of derivatives of 5-membered pyrrolo[3,4-b]indol-3(4H)-one and 6-membered pyridazino[4,5-b]indol-4(5H)-one.

Anti-zika virus agents and viral RdRp enzymatic inhibitors of derivatives of 5-membered pyrrolo[3,4-b]indol-3(4H)-one and 6-membered pyridazino[4,5-b]indol-4(5H)-one.

Journal: European journal of medicinal chemistry

Published: December 15, 2025

Design and synthesis of lactam analogs of andrographolide and discovery of their anticancer activity as dual EGFR and VEGFR2 inhibitors.

Design and synthesis of lactam analogs of andrographolide and discovery of their anticancer activity as dual EGFR and VEGFR2 inhibitors.

Journal: European journal of medicinal chemistry

Published: June 06, 2025

Corrigendum to "Discovery of ZFD-10 of a pyridazino[4,5-b]indol-4(5H)-one derivative as an anti-ZIKV agent and a ZIKV NS5 RdRp inhibitor" [Antivir. Res. 214 (2023) 105607].

Corrigendum to "Discovery of ZFD-10 of a pyridazino[4,5-b]indol-4(5H)-one derivative as an anti-ZIKV agent and a ZIKV NS5 RdRp inhibitor" [Antivir. Res. 214 (2023) 105607].

Journal: Antiviral research

Published: October 29, 2024

Anti-metastatic effects of AGS-30 on breast cancer through the inhibition of M2-like macrophage polarization.

Anti-metastatic effects of AGS-30 on breast cancer through the inhibition of M2-like macrophage polarization.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: November 07, 2023

Discovery of a fused bicyclic derivative of 4-hydroxypyrrolidine and imidazolidinone as a new anti-HCV agent.

Discovery of a fused bicyclic derivative of 4-hydroxypyrrolidine and imidazolidinone as a new anti-HCV agent.

Journal: Virology

Published: February 22, 2023

Discovery of ZFD-10 of a pyridazino[4,5-b]indol-4(5H)-one derivative as an anti-ZIKV agent and a ZIKV NS5 RdRp inhibitor.

Discovery of ZFD-10 of a pyridazino[4,5-b]indol-4(5H)-one derivative as an anti-ZIKV agent and a ZIKV NS5 RdRp inhibitor.

Journal: Antiviral research

Published: February 05, 2023

Exploration of novel hexahydropyrrolo[1,2-e]imidazol-1-one derivatives as antiviral agents against ZIKV and USUV.

Exploration of novel hexahydropyrrolo[1,2-e]imidazol-1-one derivatives as antiviral agents against ZIKV and USUV.

Journal: European journal of medicinal chemistry

Published: October 20, 2022

Antiviral effects of the fused tricyclic derivatives of indoline and imidazolidinone on ZIKV infection and RdRp activities of ZIKV and DENV.

Antiviral effects of the fused tricyclic derivatives of indoline and imidazolidinone on ZIKV infection and RdRp activities of ZIKV and DENV.

Journal: Virus research

Published: July 25, 2022

Discovery of dehydroandrographolide derivatives with C19 hindered ether as potent anti-ZIKV agents with inhibitory activities to MTase of ZIKV NS5.

Discovery of dehydroandrographolide derivatives with C19 hindered ether as potent anti-ZIKV agents with inhibitory activities to MTase of ZIKV NS5.

Journal: European journal of medicinal chemistry

Published: June 29, 2022

Discovery of Novel Andrographolide Derivatives as Antiviral Inhibitors against Human Enterovirus A71.

Discovery of Novel Andrographolide Derivatives as Antiviral Inhibitors against Human Enterovirus A71.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: December 20, 2021

Synthesis and Characterization of Andrographolide Derivatives as Regulators of βAPP Processing in Human Cells.

Synthesis and Characterization of Andrographolide Derivatives as Regulators of βAPP Processing in Human Cells.

Journal: Molecules (Basel, Switzerland)

Published: November 18, 2021

Design, synthesis, discovery and SAR of the fused tricyclic derivatives of indoline and imidazolidinone against DENV replication and infection.

Design, synthesis, discovery and SAR of the fused tricyclic derivatives of indoline and imidazolidinone against DENV replication and infection.

Journal: Bioorganic chemistry

Published: October 16, 2021

Showing 1-12 of 30

Last Updated: 09/26/2026