Guo-qiang W. Lin

1200 Cailun Road
Shanghai, 201203, China

Last Updated: 09/26/2026

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Found 107 publications

Heterologous Expression of an Abandoned Termite Mound Fungus Gene Cluster Reveals a Protective Aldehyde-Alcohol Cycle and a Candidate Termiticidal Metabolite.

Heterologous Expression of an Abandoned Termite Mound Fungus Gene Cluster Reveals a Protective Aldehyde-Alcohol Cycle and a Candidate Termiticidal Metabolite.

Journal: ACS synthetic biology

Published: July 06, 2026

Structure-Based Design and Optimization of Novel PHGDH Inhibitors for Overcoming Erlotinib-Resistant Lung Cancer.

Structure-Based Design and Optimization of Novel PHGDH Inhibitors for Overcoming Erlotinib-Resistant Lung Cancer.

Journal: Journal of medicinal chemistry

Published: June 09, 2026

Preclinical evaluation of a fluorinated bifendate derivative in triple-negative breast cancer: integrated in vitro and in vivo evidence of antitumor activity.

Preclinical evaluation of a fluorinated bifendate derivative in triple-negative breast cancer: integrated in vitro and in vivo evidence of antitumor activity.

Journal: BMC cancer

Published: April 10, 2026

Chirality-dependent toxicity decoupling: Discovery of a resibufogenin-based L-configured STING inhibitor with superior therapeutic profile for ulcerative colitis.

Chirality-dependent toxicity decoupling: Discovery of a resibufogenin-based L-configured STING inhibitor with superior therapeutic profile for ulcerative colitis.

Journal: European journal of medicinal chemistry

Published: March 10, 2026

Synthesis and Biological Evaluation of RBG Derivatives as Nrf2 Activators for the Treatment of Parkinson's Disease.

Synthesis and Biological Evaluation of RBG Derivatives as Nrf2 Activators for the Treatment of Parkinson's Disease.

Journal: International journal of molecular sciences

Published: March 03, 2026

Targeting Toll-like Receptors 7, 8, and 9 Inhibition in Systemic Lupus Erythematosus: Therapeutic Advance and Future Directions.

Targeting Toll-like Receptors 7, 8, and 9 Inhibition in Systemic Lupus Erythematosus: Therapeutic Advance and Future Directions.

Journal: Journal of medicinal chemistry

Published: February 17, 2026

Discovery of Novel NMR-Based Biomarkers and Interpretable Machine Learning Models for Risk Prediction of Rheumatoid Arthritis.

Discovery of Novel NMR-Based Biomarkers and Interpretable Machine Learning Models for Risk Prediction of Rheumatoid Arthritis.

Journal: Metabolites

Published: January 22, 2026

Traditional medicine-derived natural products as anti-osteoporotic Agents: A review on structural modifications, mechanisms, and structure-activity relationships.

Traditional medicine-derived natural products as anti-osteoporotic Agents: A review on structural modifications, mechanisms, and structure-activity relationships.

Journal: European journal of medicinal chemistry

Published: January 16, 2026

Outcompeting hydrofunctionalization: Asymmetric remote substitution of alkynes.

Outcompeting hydrofunctionalization: Asymmetric remote substitution of alkynes.

Journal: Science advances

Published: December 10, 2025

Resibufogenin promotes angiogenesis via the VAV3-mediated ITGA5-VEGF signaling axis in macrophages to alleviate myocardial infarction.

Resibufogenin promotes angiogenesis via the VAV3-mediated ITGA5-VEGF signaling axis in macrophages to alleviate myocardial infarction.

Journal: Acta pharmacologica Sinica

Published: November 27, 2025

Dysregulated high-density lipoprotein and low-density lipoprotein subfractions increase metabolic dysfunction-associated steatotic liver disease risk: a study of patients across body mass index categories.

Dysregulated high-density lipoprotein and low-density lipoprotein subfractions increase metabolic dysfunction-associated steatotic liver disease risk: a study of patients across body mass index categories.

Journal: Frontiers in nutrition

Published: November 02, 2025

Resibufogenin ameliorates cerebral ischemia-reperfusion injury by modulating microglial redox homeostasis via Keap1-Nrf2-TFR1/ARE axis.

Resibufogenin ameliorates cerebral ischemia-reperfusion injury by modulating microglial redox homeostasis via Keap1-Nrf2-TFR1/ARE axis.

Journal: Acta pharmacologica Sinica

Published: June 19, 2025

Showing 1-12 of 107

Last Updated: 09/26/2026