Guo Zhang

Cancer Center And State Key Laboratory Of Biotherapy
Chengdu, China

Last Updated: 09/26/2026

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Found 20 publications

Discovery of a Potent and Selective Cell-Active Inhibitor of Histidine-N1 Methyltransferase METTL9.

Discovery of a Potent and Selective Cell-Active Inhibitor of Histidine-N1 Methyltransferase METTL9.

Journal: Angewandte Chemie (International ed. in English)

Published: January 16, 2026

Author Correction: An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo.

Author Correction: An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo.

Journal: Nature communications

Published: December 15, 2025

Discovery of 4-((quinolin-8-ylthio)methyl)benzamide derivatives as a new class of SARS-CoV-2 nsp13 inhibitors.

Discovery of 4-((quinolin-8-ylthio)methyl)benzamide derivatives as a new class of SARS-CoV-2 nsp13 inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: January 27, 2025

An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo.

An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo.

Journal: Research square

Published: November 28, 2024

A deep learning model for structure-based bioactivity optimization and its application in the bioactivity optimization of a SARS-CoV-2 main protease inhibitor.

A deep learning model for structure-based bioactivity optimization and its application in the bioactivity optimization of a SARS-CoV-2 main protease inhibitor.

Journal: European journal of medicinal chemistry

Published: November 19, 2024

An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo.

An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo.

Journal: Nature communications

Published: November 14, 2024

Cloud computing convergence: integrating computer applications and information management for enhanced efficiency.

Cloud computing convergence: integrating computer applications and information management for enhanced efficiency.

Journal: Frontiers in big data

Published: October 08, 2024

Discovery of 5-((1H-indazol-3-yl) methylene)-2-thioxoimidazolidin-4-one derivatives as a new class of AHR agonists with anti-psoriasis activity in a mouse model.

Discovery of 5-((1H-indazol-3-yl) methylene)-2-thioxoimidazolidin-4-one derivatives as a new class of AHR agonists with anti-psoriasis activity in a mouse model.

Journal: Bioorganic & medicinal chemistry letters

Published: May 21, 2023

Discovery of 3-phenyl-1,2,4-oxadiazole derivatives as a new class of SARS-CoV-2 main protease inhibitors.

Discovery of 3-phenyl-1,2,4-oxadiazole derivatives as a new class of SARS-CoV-2 main protease inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: December 19, 2022

Non-classical ferroptosis inhibition by a small molecule targeting PHB2.

Non-classical ferroptosis inhibition by a small molecule targeting PHB2.

Journal: Nature communications

Published: May 24, 2022

Discovery of 2-vinyl-10H-phenothiazine derivatives as a class of ferroptosis inhibitors with minimal human Ether-a-go-go related gene (hERG) activity for the treatment of DOX-induced cardiomyopathy.

Discovery of 2-vinyl-10H-phenothiazine derivatives as a class of ferroptosis inhibitors with minimal human Ether-a-go-go related gene (hERG) activity for the treatment of DOX-induced cardiomyopathy.

Journal: Bioorganic & medicinal chemistry letters

Published: April 13, 2022

Identification of triazolopyridine derivatives as a new class of AhR agonists and evaluation of anti-psoriasis effect in a mouse model.

Identification of triazolopyridine derivatives as a new class of AhR agonists and evaluation of anti-psoriasis effect in a mouse model.

Journal: European journal of medicinal chemistry

Published: November 09, 2021

Showing 1-12 of 20

Last Updated: 09/26/2026