Guocai Q. Wang

State Key Laboratory Of Bioactive Molecules And Druggability Assessment
Guangzhou, China

Last Updated: 09/26/2026

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Found 25 publications

ROS-driven mitophagy arrest mediates the anti-glioblastoma activity of Molephantin.

ROS-driven mitophagy arrest mediates the anti-glioblastoma activity of Molephantin.

Journal: Autophagy

Published: May 06, 2026

EM2, a Natural Product MST1/2 Kinase Activator, Suppresses Non-Small Cell Lung Cancer via Hippo Pathway Activation.

EM2, a Natural Product MST1/2 Kinase Activator, Suppresses Non-Small Cell Lung Cancer via Hippo Pathway Activation.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: June 11, 2025

AI-identified CD133-targeting natural compounds demonstrate differential anti-tumor effects and mechanisms in pan-cancer models.

AI-identified CD133-targeting natural compounds demonstrate differential anti-tumor effects and mechanisms in pan-cancer models.

Journal: EMBO molecular medicine

Published: February 28, 2025

Advances, challenges and future applications of liver organoids in experimental regenerative medicine.

Advances, challenges and future applications of liver organoids in experimental regenerative medicine.

Journal: Frontiers in medicine

Published: November 05, 2024

Structurally novel tryptamine-derived alkaloids from the seeds of Peganum harmala and their antiviral activities against respiratory syncytial virus.

Structurally novel tryptamine-derived alkaloids from the seeds of Peganum harmala and their antiviral activities against respiratory syncytial virus.

Journal: Chinese journal of natural medicines

Published: September 23, 2024

Small-molecule Molephantin induces apoptosis and mitophagy flux blockage through ROS production in glioblastoma.

Small-molecule Molephantin induces apoptosis and mitophagy flux blockage through ROS production in glioblastoma.

Journal: Cancer letters

Published: February 27, 2024

New acylphloroglucinol-sesquiterpenoid adducts with antiviral activities from Dryopteris atrata.

New acylphloroglucinol-sesquiterpenoid adducts with antiviral activities from Dryopteris atrata.

Journal: Chinese journal of natural medicines

Published: December 26, 2023

Discovery of cyperenoic acid as a potent and novel entry inhibitor of influenza A virus.

Discovery of cyperenoic acid as a potent and novel entry inhibitor of influenza A virus.

Journal: Antiviral research

Published: October 12, 2023

A Novel Aniline Derivative from Peganum harmala L. Promoted Apoptosis via Activating PI3K/AKT/mTOR-Mediated Autophagy in Non-Small Cell Lung Cancer Cells.

A Novel Aniline Derivative from Peganum harmala L. Promoted Apoptosis via Activating PI3K/AKT/mTOR-Mediated Autophagy in Non-Small Cell Lung Cancer Cells.

Journal: International journal of molecular sciences

Published: June 21, 2023

Sophflarine A, a novel matrine-derived alkaloid from Sophora flavescens with therapeutic potential for non-small cell lung cancer through ROS-mediated pyroptosis and autophagy.

Sophflarine A, a novel matrine-derived alkaloid from Sophora flavescens with therapeutic potential for non-small cell lung cancer through ROS-mediated pyroptosis and autophagy.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: January 18, 2023

Targeting VCP potentiates immune checkpoint therapy for colorectal cancer.

Targeting VCP potentiates immune checkpoint therapy for colorectal cancer.

Journal: Cell reports

Published: January 11, 2023

IDH1 mutation impairs antiviral response and potentiates oncolytic virotherapy in glioma.

IDH1 mutation impairs antiviral response and potentiates oncolytic virotherapy in glioma.

Journal: Nature communications

Published: November 01, 2022

Showing 1-12 of 25

Last Updated: 09/26/2026