Guodi Cai

Guangzhou, 510006, China

Last Updated: 09/26/2026

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Found 19 publications

Discovery of a Potent RXRγ Degrader WCF-598 for the Treatment of Castration-Resistant Prostate Cancer.

Discovery of a Potent RXRγ Degrader WCF-598 for the Treatment of Castration-Resistant Prostate Cancer.

Journal: Journal of medicinal chemistry

Published: March 20, 2026

Single-cell profiling of tumor lineage plasticity and the immune microenvironment in transformed small cell lung cancer.

Single-cell profiling of tumor lineage plasticity and the immune microenvironment in transformed small cell lung cancer.

Journal: Journal of translational medicine

Published: October 29, 2025

RORγ drives non-small cell lung cancer progression by upregulating the NGF signaling.

RORγ drives non-small cell lung cancer progression by upregulating the NGF signaling.

Journal: Respiratory research

Published: October 28, 2025

FGF1-FGFR2 axis regulated by nuclear receptor RORγ represents an effective strategy in intrahepatic cholangiocarcinoma.

FGF1-FGFR2 axis regulated by nuclear receptor RORγ represents an effective strategy in intrahepatic cholangiocarcinoma.

Journal: Cell death discovery

Published: July 26, 2025

Discovery of highly potent marine-derived compound Penicolinate H reveals SREBP-1 mediated lipogenesis as a druggable vulnerability in gastric cancer.

Discovery of highly potent marine-derived compound Penicolinate H reveals SREBP-1 mediated lipogenesis as a druggable vulnerability in gastric cancer.

Journal: Journal of translational medicine

Published: June 05, 2025

RORγ Hijacks HIF1α to Promote Peritoneal Metastasis of Gastric Cancer.

RORγ Hijacks HIF1α to Promote Peritoneal Metastasis of Gastric Cancer.

Journal: Cancer research

Published: April 18, 2025

UMP functions as an endogenous regulator of NR4A1 to control gastric cancer progression.

UMP functions as an endogenous regulator of NR4A1 to control gastric cancer progression.

Journal: Molecular cell

Published: December 03, 2024

Therapeutic targeting ERRγ suppresses metastasis via extracellular matrix remodeling in small cell lung cancer.

Therapeutic targeting ERRγ suppresses metastasis via extracellular matrix remodeling in small cell lung cancer.

Journal: EMBO molecular medicine

Published: January 26, 2024

Small protein ERSP encoded by LINC02870 promotes triple negative breast cancer progression via IRE1α/XBP1s activation.

Small protein ERSP encoded by LINC02870 promotes triple negative breast cancer progression via IRE1α/XBP1s activation.

Journal: Cell death and differentiation

Published: January 25, 2024

Targeting KPNB1 with genkwadaphnin suppresses gastric cancer progression through the Nur77-mediated signaling pathway.

Targeting KPNB1 with genkwadaphnin suppresses gastric cancer progression through the Nur77-mediated signaling pathway.

Journal: European journal of pharmacology

Published: January 09, 2024

Targeting RORγ inhibits the growth and metastasis of hepatocellular carcinoma.

Targeting RORγ inhibits the growth and metastasis of hepatocellular carcinoma.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: July 08, 2023

Tumor mitochondrial oxidative phosphorylation stimulated by the nuclear receptor RORγ represents an effective therapeutic opportunity in osteosarcoma.

Tumor mitochondrial oxidative phosphorylation stimulated by the nuclear receptor RORγ represents an effective therapeutic opportunity in osteosarcoma.

Journal: Cell reports. Medicine

Published: March 08, 2023

Showing 1-12 of 19

Last Updated: 09/26/2026