Guofang Bi

NMPA Key Laboratory For Research And Evaluation Of Drug Metabolism & Guangdong Provincial Key Laboratory Of New Drug Screening & Guangdong Hong Kong Macao Joint Laboratory For New Drug Screening
Guangzhou, China

Last Updated: 09/26/2026

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Found 14 publications

Gut microbiota affects the role of mPXR agonist PCN in alleviating sepsis-induced liver injury by regulating YAP activation.

Gut microbiota affects the role of mPXR agonist PCN in alleviating sepsis-induced liver injury by regulating YAP activation.

Journal: International immunopharmacology

Published: October 09, 2025

PXR activation ameliorates hyperuricemic nephropathy via NRF2 signaling.

PXR activation ameliorates hyperuricemic nephropathy via NRF2 signaling.

Journal: Pharmacological research

Published: June 28, 2025

Constitutive androstane receptor activation modulates YAP expression and activity through ubiquitination and sumoylation.

Constitutive androstane receptor activation modulates YAP expression and activity through ubiquitination and sumoylation.

Journal: Toxicology letters

Published: April 23, 2025

Assessment of the in vitro cytochrome P450 activity in human liver organoids: Development and validation of a cocktail method with liquid chromatography-tandem mass spectrometry.

Assessment of the in vitro cytochrome P450 activity in human liver organoids: Development and validation of a cocktail method with liquid chromatography-tandem mass spectrometry.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: March 06, 2025

Development and Validation of a HPLC-MS/MS Method for the Determination of Compound 13b in Rat Plasma and Its Application to a Pharmacokinetic Study.

Development and Validation of a HPLC-MS/MS Method for the Determination of Compound 13b in Rat Plasma and Its Application to a Pharmacokinetic Study.

Journal: Biomedical chromatography : BMC

Published: January 22, 2025

Exosomes From Intestinal Epithelial Cells Promote Hepatic Differentiation of Liver Progenitor Cells in Gut-Liver-on-a-Chip Models.

Exosomes From Intestinal Epithelial Cells Promote Hepatic Differentiation of Liver Progenitor Cells in Gut-Liver-on-a-Chip Models.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: December 24, 2024

PPARα regulates YAP protein levels and activity by affecting its ubiquitination modification.

PPARα regulates YAP protein levels and activity by affecting its ubiquitination modification.

Journal: BMC biology

Published: October 23, 2024

Development and Validation of a Sensitive LC-MS/MS Method for Determination of Lenvatinib and Its Major Metabolites in Human Plasma and Its Application in Hepatocellular Carcinoma Patients.

Development and Validation of a Sensitive LC-MS/MS Method for Determination of Lenvatinib and Its Major Metabolites in Human Plasma and Its Application in Hepatocellular Carcinoma Patients.

Journal: Journal of separation science

Published: September 03, 2024

Pregnane X receptor activation promotes hematopoiesis during liver regeneration by inducing proliferation of hematopoietic stem and progenitor cells in mice.

Pregnane X receptor activation promotes hematopoiesis during liver regeneration by inducing proliferation of hematopoietic stem and progenitor cells in mice.

Journal: Pharmacological research

Published: August 06, 2024

Schisandrol B alleviates depression-like behavior in mice by regulating bile acid homeostasis in the brain-liver-gut axis via the pregnane X receptor.

Schisandrol B alleviates depression-like behavior in mice by regulating bile acid homeostasis in the brain-liver-gut axis via the pregnane X receptor.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: August 03, 2024

Parabacteroides distasonis promotes liver regeneration by increasing β-hydroxybutyric acid (BHB) production and BHB-driven STAT3 signals.

Parabacteroides distasonis promotes liver regeneration by increasing β-hydroxybutyric acid (BHB) production and BHB-driven STAT3 signals.

Journal: Acta pharmaceutica Sinica. B

Published: August 01, 2024

Pregnane X receptor activation induces liver enlargement and regeneration and simultaneously promotes the metabolic activity of CYP3A1/2 and CYP2C6/11 in rats.

Pregnane X receptor activation induces liver enlargement and regeneration and simultaneously promotes the metabolic activity of CYP3A1/2 and CYP2C6/11 in rats.

Journal: Basic & clinical pharmacology & toxicology

Published: February 07, 2024

Showing 1-12 of 14

Last Updated: 09/26/2026